The Chemical Identity of 7-Nitroisoquinoline: Properties and Potential
In the intricate world of chemical compounds, understanding the fundamental properties of a molecule is the first step towards unlocking its full potential. 7-Nitroisoquinoline, identified by CAS number 13058-73-6, is a fascinating heterocyclic organic compound that has garnered considerable attention for its utility in synthetic chemistry and its emerging roles in various research fields.
Chemically, 7-Nitroisoquinoline is characterized by its molecular formula C9H6N2O2 and a molecular weight of approximately 174.16 g/mol. The core structure is that of isoquinoline, a bicyclic aromatic system comprising a benzene ring fused with a pyridine ring. The addition of a nitro group (-NO2) at the 7-position significantly influences its electronic distribution and reactivity. Physically, it typically presents as a yellow to brown solid, a common observation for many nitroaromatic compounds. Its melting point, generally reported in the range of 177-178 °C, indicates a stable solid form at room temperature. Purity levels of 97% or higher are often specified for research and pharmaceutical applications, underscoring the importance of precise manufacturing processes by manufacturers.
The reactivity of 7-Nitroisoquinoline is primarily shaped by the electron-withdrawing nature of the nitro group. While this group deactivates the aromatic ring towards electrophilic substitution, it also activates the molecule for other transformations. The most significant of these is the reduction of the nitro group to an amine. This reduction yields 7-aminoisoquinoline, a highly versatile intermediate that serves as a precursor for a wide array of functionalized isoquinoline derivatives. These derivatives are of great interest in medicinal chemistry due to the prevalence of the isoquinoline scaffold in bioactive natural products and pharmaceuticals.
Beyond its role as a synthetic intermediate, research has begun to explore the intrinsic biological activities of 7-Nitroisoquinoline and its closely related analogs. Studies have indicated potential applications in areas such as anticancer research, where derivatives may induce apoptosis in cancer cells. Its potential as an antimicrobial agent and its exploration in anti-HIV drug development further highlight its multifaceted nature. While these applications are still largely in the research phase, they point to a broader potential for compounds derived from this scaffold.
For researchers and procurement specialists looking to leverage these properties, sourcing from reliable suppliers is crucial. Understanding the detailed specifications, including purity, appearance, and stability, is essential. When considering where to buy, factors like batch consistency, technical support, and competitive price points offered by established chemical providers, especially those with strong manufacturing bases, are key considerations.
In summary, 7-Nitroisoquinoline (CAS 13058-73-6) is a compound with a well-defined chemical identity and a promising outlook. Its predictable reactivity, coupled with potential direct biological activities, positions it as a valuable asset in the ongoing exploration of new chemical entities for scientific and pharmaceutical advancement. Engaging with reputable chemical providers ensures access to material that meets the stringent demands of modern research.
Perspectives & Insights
Agile Reader One
“Physically, it typically presents as a yellow to brown solid, a common observation for many nitroaromatic compounds.”
Logic Vision Labs
“Its melting point, generally reported in the range of 177-178 °C, indicates a stable solid form at room temperature.”
Molecule Origin 88
“Purity levels of 97% or higher are often specified for research and pharmaceutical applications, underscoring the importance of precise manufacturing processes by manufacturers.”