The Chemical Profile of (2S)-2-Indolinecarboxylic Acid: Properties for Synthesis
Understanding the fundamental chemical and physical properties of an intermediate is essential for its effective utilization in synthesis. (2S)-2-Indolinecarboxylic acid (CAS: 78348-24-0) is a prime example of a compound whose specific attributes make it highly sought after in the pharmaceutical and fine chemical industries. As a premier supplier, NINGBO INNO PHARMCHEM CO.,LTD. provides detailed information to support your R&D and procurement efforts.
The compound is identified by its CAS number 78348-24-0 and presents as a white crystalline powder. Its molecular formula is C9H9NO2, with a molecular weight of approximately 163.173 g/mol. A key characteristic for synthesis is its melting point, which is reported as 168°C with decomposition (lit.). This indicates that the compound is stable under typical storage conditions but requires careful handling at elevated temperatures during reaction processes. The appearance as a pure white crystalline powder signifies a level of refinement often sought in pharmaceutical intermediates, suggesting efficient purification during its manufacturing.
Further chemical data includes its EINECS number (278-899-6), providing a unique identifier for regulatory and inventory purposes. The structure of (2S)-2-Indolinecarboxylic acid features a saturated indoline ring system with a carboxylic acid group at the chiral center (position 2). This specific enantiomeric form, denoted by '(2S)', is critical for applications where stereoselectivity is required, particularly in the synthesis of chiral drugs.
When considering the synthesis applications, the reactivity of the carboxylic acid group allows for various derivatizations, such as esterification, amidation, or reduction. The indoline nitrogen can also be a site for further functionalization. For researchers looking to buy (2S)-2-Indolinecarboxylic acid, these properties highlight its versatility as a building block. As a manufacturer and supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. ensures that the material we provide consistently meets these described chemical profiles, enabling seamless integration into complex synthetic routes. We aim to be your go-to source for high-quality pharmaceutical intermediates, facilitating your scientific advancements.
Perspectives & Insights
Chem Catalyst Pro
“The structure of (2S)-2-Indolinecarboxylic acid features a saturated indoline ring system with a carboxylic acid group at the chiral center (position 2).”
Agile Thinker 7
“This specific enantiomeric form, denoted by '(2S)', is critical for applications where stereoselectivity is required, particularly in the synthesis of chiral drugs.”
Logic Spark 24
“When considering the synthesis applications, the reactivity of the carboxylic acid group allows for various derivatizations, such as esterification, amidation, or reduction.”