Understanding the precise chemical properties and synthesis pathways of specialized reagents is fundamental for chemists and researchers. Fmoc-Phe-OPfp, or N-Fmoc-L-phenylalanine pentafluorophenyl ester, is a crucial amino acid derivative utilized extensively in peptide synthesis. NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated manufacturer, provides key insights into this compound's profile.

Chemical Identity and Specifications

Fmoc-Phe-OPfp is characterized by:

  • Chemical Name: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoic acid pentafluorophenyl ester
  • CAS Number: 86060-92-6. This unique identifier is essential for unambiguous identification in databases and regulatory documentation.
  • Molecular Formula: C30H20F5NO4. This formula reveals the elemental composition of the molecule.
  • Molecular Weight: Approximately 553.5 g/mol. This value is important for stoichiometric calculations in synthesis.
  • Appearance: Typically supplied as a white to off-white powder, indicating its physical state.

Synthesis and Reactivity

The synthesis of Fmoc-Phe-OPfp involves protecting the amino group of L-phenylalanine with the Fmoc moiety, followed by activation of the carboxylic acid group with pentafluorophenol. The pentafluorophenyl ester moiety is an excellent leaving group, making the carboxyl group highly electrophilic. This activation is the key to its utility in forming peptide bonds efficiently during Solid Phase Peptide Synthesis (SPPS) and other amide bond-forming reactions.

Why Choose NINGBO INNO PHARMCHEM CO.,LTD. for Your Fmoc-Phe-OPfp Needs?

As a leading manufacturer and supplier of fine chemicals, NINGBO INNO PHARMCHEM CO.,LTD. specializes in producing high-purity Fmoc-Phe-OPfp. We ensure our product meets rigorous quality standards, crucial for sensitive chemical synthesis and pharmaceutical applications. When you buy Fmoc-Phe-OPfp from us, you are assured of:

  • Guaranteed Purity: We typically offer purities exceeding 98%, validated through analytical techniques like HPLC and NMR.
  • Reliable Production: Our manufacturing capabilities allow for consistent production and supply, meeting both research and bulk order demands.
  • Competitive Sourcing: As a Chinese manufacturer, we provide cost-effective solutions without compromising on quality.

For any researcher or procurement specialist looking for detailed specifications or to source Fmoc-Phe-OPfp, our company is a trusted partner. We invite you to request a quote and discover how our commitment to chemical excellence can support your projects.