Understanding the intrinsic properties of chemical intermediates is fundamental for successful organic synthesis. 3,4-Difluorotoluene (CAS: 2927-34-6) is a compound that draws attention for its distinct physical and chemical characteristics, making it a valuable asset in research laboratories and industrial production alike. As a premier manufacturer and supplier, we provide insights into why this compound is a preferred choice for many synthetic chemists.

Physically, 3,4-Difluorotoluene presents as a colorless to light yellow transparent liquid. Its notable physical properties include a boiling point of approximately 110-113 °C and a density of around 1.12 g/mL at 25 °C. The refractive index is approximately n20/D 1.45. Crucially, it possesses a flash point of 77 °F, classifying it as a flammable liquid, which necessitates appropriate handling and storage precautions. Its insolubility in water is a common trait for many aromatic hydrocarbons, influencing solvent selection in reaction setups.

Chemically, the presence of two fluorine atoms on the toluene ring significantly influences its reactivity. These fluorine atoms are electron-withdrawing, affecting the electron density distribution in the aromatic system. This electronic influence can direct electrophilic aromatic substitution reactions and modify the reactivity of the methyl group. The compound is highly regarded as a versatile building block in organic synthesis, particularly for the introduction of difluorotolyl moieties into more complex molecular architectures. Researchers often seek out this intermediate to synthesize fluorinated analogs of existing molecules or to explore entirely new chemical entities.

The synthesis applications are broad, spanning the creation of novel pharmaceuticals, agrochemicals, and specialty materials. For instance, its use as a pharmaceutical intermediate involves incorporating the difluorotoluene structure into drug candidates to enhance their biological activity or pharmacokinetic properties. In agrochemical research, it serves a similar role in developing more effective and stable pesticides and herbicides. When you are looking to buy 3,4-Difluorotoluene, partnering with a reputable manufacturer and supplier in China ensures you receive a product that meets stringent purity requirements (≥98%), guaranteeing reliable performance in your synthetic endeavors. We invite you to connect with us to learn more about sourcing this essential organic intermediate.