In the intricate world of chemical synthesis, understanding the properties of key intermediates is fundamental to unlocking their full potential. 2-Bromo-5-fluoropyridine (CAS 144100-07-2) is a prime example of such a compound, offering a unique blend of chemical reactivity and structural features that make it indispensable across various scientific disciplines, particularly in pharmaceuticals and agrochemicals.

At its core, 2-Bromo-5-fluoropyridine is a heterocyclic organic compound belonging to the pyridine family. Its chemical formula is C5H3BrFN, with a molecular weight of approximately 175.99 g/mol. The molecule is characterized by a pyridine ring substituted with a bromine atom at the 2-position and a fluorine atom at the 5-position. This specific arrangement of halogen atoms imparts distinct electronic and steric properties. The bromine atom serves as an excellent leaving group, making the molecule highly amenable to a variety of metal-catalyzed cross-coupling reactions, such as Suzuki-Miyaura, Sonogashira, and Stille couplings. These reactions are critical for forming new carbon-carbon bonds, enabling the construction of complex molecular frameworks.

The fluorine atom, being highly electronegative, influences the electron distribution within the pyridine ring, often activating or deactivating certain positions for electrophilic or nucleophilic attack. This can lead to enhanced reactivity or altered regioselectivity in subsequent synthetic steps. Furthermore, the incorporation of fluorine into organic molecules is a well-established strategy in medicinal chemistry to modify properties such as lipophilicity, metabolic stability, and binding affinity to biological targets. Thus, 2-Bromo-5-fluoropyridine is frequently employed as a key building block in the development of novel pharmaceuticals and agrochemicals designed for enhanced performance and efficacy.

As a sought-after intermediate, sourcing high-purity 2-Bromo-5-fluoropyridine is paramount. Manufacturers in China are major suppliers, offering this compound typically as a white powder or solid with a purity exceeding 99%. When you choose to buy 2-Bromo-5-fluoropyridine, selecting a reputable manufacturer ensures that you receive a product that meets rigorous quality standards. This is crucial for reproducible synthesis and achieving desired outcomes in your research or production processes. We are a dedicated supplier, offering this vital chemical at competitive price points, alongside comprehensive technical support.

In conclusion, the chemical properties of 2-Bromo-5-fluoropyridine (CAS 144100-07-2) make it an exceptionally valuable intermediate for organic chemists. Its utility in cross-coupling reactions and the influence of its halogen substituents open doors to creating advanced molecules for diverse applications. For reliable access to this essential chemical, consider partnering with experienced manufacturers and suppliers.