The Chemical Properties and Synthetic Utility of 4-Bromobenzeneboronic Acid
Understanding the nuanced chemical properties of key intermediates is fundamental to successful organic synthesis. 4-Bromobenzeneboronic acid (CAS 5467-74-3) is a prime example of such a compound, offering a unique combination of reactivity and structural features that make it indispensable in modern chemical research and industrial applications. NINGBO INNO PHARMCHEM CO.,LTD. supplies this crucial organic synthesis building block with a high purity of 97% minimum, ensuring its efficacy in demanding synthetic protocols.
The molecular structure of 4-Bromobenzeneboronic acid features a benzene ring substituted with both a bromine atom and a boronic acid group (-B(OH)2) at opposite positions. This arrangement dictates its chemical behavior. The bromine atom serves as an excellent leaving group in various cross-coupling reactions, most notably the Suzuki-Miyaura coupling, which is a cornerstone of modern synthetic organic chemistry. This reaction allows for the formation of new carbon-carbon bonds by coupling the aryl halide with an organoboron compound in the presence of a palladium catalyst and a base. The boronic acid moiety itself can also participate in other reactions or be transformed into different functional groups.
The physical characteristics of 4-Bromobenzeneboronic acid further contribute to its utility. It typically presents as an off-white powder, with solubility primarily in polar organic solvents like methanol, while remaining insoluble in water. This differential solubility can be advantageous in reaction work-ups and purifications, allowing chemists to efficiently isolate the desired products. The melting point, reported in the range of 284-288℃ (lit.), indicates a stable solid form.
The synthetic utility of 4-Bromobenzeneboronic acid is vast. It is widely employed as a critical intermediate in the synthesis of OLED materials, where precise molecular engineering is necessary to achieve specific optoelectronic properties. In this context, it facilitates the construction of complex conjugated systems that are responsible for light emission and charge transport within OLED devices. Similarly, in the pharmaceutical industry, this compound serves as a vital building block for creating complex drug molecules. Its ability to introduce a functionalized phenyl ring into larger structures makes it invaluable for designing novel chemical entities with potential therapeutic activities.
For those looking to buy 4-Bromobenzeneboronic acid, NINGBO INNO PHARMCHEM CO.,LTD. offers a reliable source for this high-purity compound. Our commitment to quality ensures that researchers and manufacturers can confidently integrate this versatile intermediate into their synthetic strategies, driving innovation in both electronic materials and life sciences. Exploring the full synthetic potential of this organoboron compound opens doors to groundbreaking discoveries.
Perspectives & Insights
Molecule Vision 7
“Exploring the full synthetic potential of this organoboron compound opens doors to groundbreaking discoveries.”
Alpha Origin 24
“Understanding the nuanced chemical properties of key intermediates is fundamental to successful organic synthesis.”
Future Analyst X
“4-Bromobenzeneboronic acid (CAS 5467-74-3) is a prime example of such a compound, offering a unique combination of reactivity and structural features that make it indispensable in modern chemical research and industrial applications.”