The Chemical Significance of 2-Amino-3-nitrobenzamide in Organic Synthesis
Organic synthesis is the art and science of constructing complex molecules from simpler ones. At the heart of this discipline lie versatile chemical intermediates, compounds that serve as crucial building blocks for a vast array of end products. 2-Amino-3-nitrobenzamide (CAS: 313279-12-8) is one such intermediate, highly valued for its unique structural features and reactivity, particularly in the pharmaceutical sector. As a leading provider of fine chemicals, we are proud to offer this compound, understanding its deep significance in advancing organic chemistry.
The chemical structure of 2-Amino-3-nitrobenzamide is characterized by a benzamide core substituted with an amino group at the C2 position and a nitro group at the C3 position. This arrangement confers specific electronic and steric properties, making it an attractive precursor for a variety of synthetic transformations. Its primary application is in the synthesis of PARP-1 inhibitors, a class of compounds investigated for their role in DNA repair pathways and potential in cancer therapeutics. The presence of both an amine and a nitro group allows for diverse functionalization, enabling chemists to build intricate molecular architectures tailored for specific biological targets.
For researchers and industrial chemists looking to buy 2-Amino-3-nitrobenzamide, understanding its physical and chemical properties is key. It typically appears as an orange solid, with a melting point around 240-242 °C, indicating its stability under various conditions. Its solubility in common organic solvents like DMSO, methanol, and chloroform facilitates its use in solution-phase reactions. When you search for a reliable 2-Amino-3-nitrobenzamide supplier, it's essential to confirm these properties and the purity offered. Manufacturers often provide detailed specifications, including CAS number, molecular formula (C7H7N3O3), and molecular weight (181.15 g/mol), which are critical for accurate stoichiometric calculations in synthetic planning.
The journey from simple starting materials to complex therapeutic agents often involves multiple synthetic steps, and the choice of intermediates can significantly impact yield, purity, and cost-effectiveness. 2-Amino-3-nitrobenzamide, when sourced from a reputable manufacturer, provides a solid foundation for synthesizing advanced molecules. We are committed to providing this essential intermediate with high purity, ensuring that your synthetic routes are robust and reproducible. Whether your project involves drug discovery, agrochemical development, or materials science, this compound offers a gateway to novel molecular structures.
In conclusion, 2-Amino-3-nitrobenzamide is a testament to the power of chemical intermediates in driving innovation. Its chemical significance lies in its adaptability as a building block for high-value compounds, particularly in the pharmaceutical realm. We invite scientists and procurement specialists to consider us their trusted partner for sourcing this vital organic compound, ensuring quality and reliability for all your synthesis needs.
Perspectives & Insights
Future Origin 2025
“2-Amino-3-nitrobenzamide, when sourced from a reputable manufacturer, provides a solid foundation for synthesizing advanced molecules.”
Core Analyst 01
“We are committed to providing this essential intermediate with high purity, ensuring that your synthetic routes are robust and reproducible.”
Silicon Seeker One
“Whether your project involves drug discovery, agrochemical development, or materials science, this compound offers a gateway to novel molecular structures.”