The world of organic synthesis is constantly seeking novel and versatile building blocks to construct complex molecular architectures. Among these, heterocyclic compounds with multiple functional groups offer immense potential. 7-Bromo-2,4-dichloroquinazoline (CAS: 959237-68-4) is one such compound, distinguished by its reactive bromine and chlorine atoms on a quinazoline core. As a leading manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. highlights the chemical versatility that makes this intermediate invaluable for researchers.

7-Bromo-2,4-dichloroquinazoline, with its molecular formula C8H3BrCl2N2 and molecular weight of 277.93, is a potent intermediate due to its strategically placed substituents. The two chlorine atoms at positions 2 and 4 are highly susceptible to nucleophilic substitution reactions. This allows for the introduction of various amine, alcohol, or thiol groups, forming new C-N, C-O, or C-S bonds. Furthermore, the bromine atom at the 7-position opens doors to cross-coupling reactions, such as Suzuki, Sonogashira, or Buchwald-Hartwig couplings. These reactions enable the formation of new carbon-carbon or carbon-heteroatom bonds, allowing for the facile construction of elaborate fused ring systems or the attachment of diverse side chains.

The synthetic utility of 7-Bromo-2,4-dichloroquinazoline makes it a prime candidate for drug discovery and development programs. Researchers can purchase this compound to efficiently synthesize analogs of existing drugs or to explore entirely new chemical spaces. For example, nucleophilic displacement of the chlorine atoms with various amines can lead to diverse libraries of substituted quinazolines, many of which exhibit significant biological activities. The bromine atom can be further functionalized to introduce pharmacokinetic modifiers or target-specific functionalities. The availability of this intermediate from reliable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. ensures that researchers can obtain high-purity material (typically 98% min, beige or yellow powder) for their demanding synthetic strategies.

Beyond its role in pharmaceuticals, the reactivity profile of 7-Bromo-2,4-dichloroquinazoline suggests potential applications in material science, for instance, in the development of organic semiconductors or functional polymers where the quinazoline core can impart desirable electronic or photophysical properties. When considering the purchase of such a reactive intermediate, understanding the supplier's quality control is crucial. Manufacturers who provide detailed analytical data, such as COA and NMR, instill confidence in the material's suitability for complex synthetic endeavors. Pricing for this versatile intermediate is generally competitive when sourced in bulk from established chemical manufacturers.

In summary, the inherent chemical versatility of 7-Bromo-2,4-dichloroquinazoline, stemming from its reactive halogen substituents and quinazoline core, makes it an indispensable tool for modern organic chemists. We invite researchers and procurement professionals to explore the synthetic possibilities and to inquire about purchasing this valuable intermediate from NINGBO INNO PHARMCHEM CO.,LTD., your trusted partner in advanced chemical synthesis.