5-Bromo-1,2,3,4-tetrahydroisoquinoline (CAS 81237-69-6) is a compound that holds significant interest within the realms of organic chemistry and pharmaceutical sciences. As a leading manufacturer and supplier in China, we delve into the core chemistry and applications of this vital intermediate, explaining why it's a sought-after material for researchers and industrial chemists alike.

Structurally, 5-Bromo-1,2,3,4-tetrahydroisoquinoline features a fused bicyclic system, combining a benzene ring with a piperidine ring, further functionalized with a bromine atom at the 5-position. This specific arrangement of atoms, with the molecular formula C9H10BrN, dictates its reactivity. The bromine atom is a key functional group, capable of participating in various reactions, most notably nucleophilic substitution and palladium-catalyzed cross-coupling reactions. These reactions are fundamental to building more complex molecular architectures, making this compound an exceptionally useful pharmaceutical intermediate.

The synthesis of 5-Bromo-1,2,3,4-tetrahydroisoquinoline is a carefully controlled process. Typically, it involves electrophilic aromatic substitution on the 1,2,3,4-tetrahydroisoquinoline core. Achieving high purity, often exceeding 99%, is a testament to our advanced manufacturing techniques. When researchers decide to buy CAS 81237-69-6, they are seeking a reliable precursor that will perform predictably in their synthetic schemes. As a dedicated manufacturer, we ensure that our product meets these stringent requirements.

The applications of this brominated tetrahydroisoquinoline derivative are diverse. It serves as a crucial intermediate in the synthesis of:

  • Pharmaceuticals: Its core structure is found in numerous bioactive molecules, and the bromine atom provides a handle for attaching diverse side chains to explore new drug candidates.
  • Agrochemicals: While less common, similar heterocyclic structures find use in developing novel crop protection agents.
  • Materials Science: Functionalized heterocycles can be incorporated into advanced materials for electronic or optical applications.

For those looking to procure this chemical, understanding the global supply landscape is important. As a leading supplier in China, we offer competitive pricing and readily available stock. We encourage you to inquire about the price for bulk orders or explore our custom synthesis options if your needs are highly specific. Our goal is to be your trusted partner, providing not just chemicals, but also the expertise and reliability you need to advance your projects. Contact us today to learn more about our high-quality 5-Bromo-1,2,3,4-tetrahydroisoquinoline.