The Chemistry Behind 1-Boc-Piperidine-2-Carboxamide: Synthesis and Applications
The field of organic chemistry is constantly advancing, driven by the discovery and synthesis of novel compounds that serve as building blocks for more complex molecules. 1-Boc-Piperidine-2-Carboxamide, identified by its CAS number 388077-74-5, is one such compound that holds significant importance, particularly within pharmaceutical research and development. Understanding its chemical properties and synthetic utility is key for any chemist or procurement manager involved in its sourcing.
Chemically, 1-Boc-Piperidine-2-Carboxamide is a derivative of piperidine, a six-membered heterocyclic amine. The 'Boc' (tert-butoxycarbonyl) group serves as a protecting group for the nitrogen atom, allowing for controlled reactions at other parts of the molecule. The presence of the carboxamide group (-CONH2) on the piperidine ring at the 2-position provides a reactive site for further derivatization. This structural combination makes it a versatile intermediate for chemists looking to introduce specific functionalities into their target molecules. Its molecular formula is C11H20N2O3, with a molecular weight of approximately 228.29 g/mol.
The synthesis of 1-Boc-Piperidine-2-Carboxamide typically involves established organic chemistry methodologies, often starting from readily available piperidine derivatives. Manufacturers who specialize in custom synthesis and the production of fine chemicals can efficiently produce this compound. For buyers, knowing the typical appearance (white to off-white solid) and purity levels (often >95%) from a reputable manufacturer is vital. This ensures that the material is suitable for complex synthetic transformations without introducing unwanted impurities.
The applications of 1-Boc-Piperidine-2-Carboxamide are primarily rooted in its utility as a pharmaceutical intermediate. It is frequently employed in the synthesis of Active Pharmaceutical Ingredients (APIs) and in the development of new drug candidates. Researchers leverage its structure to build complex heterocyclic systems that are common motifs in many biologically active compounds. Therefore, when scientists are searching for this chemical, they are often engaged in drug discovery or process optimization projects.
For companies involved in the pharmaceutical supply chain, securing a consistent and high-quality source of 1-Boc-Piperidine-2-Carboxamide is essential. Manufacturers based in regions like China are prominent suppliers, offering competitive pricing and the ability to scale production. Procurement managers should always request detailed product specifications and inquire about sample availability to confirm the quality before placing larger orders. This due diligence ensures a stable supply chain for critical R&D or manufacturing processes.
In summary, 1-Boc-Piperidine-2-Carboxamide (CAS: 388077-74-5) is a valuable tool in the organic chemist's arsenal. Its well-defined chemical structure and reactivity make it a sought-after intermediate for pharmaceutical synthesis. By understanding its properties and engaging with reliable manufacturers for high-purity material, researchers can effectively utilize this compound to drive innovation in drug development.
Perspectives & Insights
Silicon Analyst 88
“The applications of 1-Boc-Piperidine-2-Carboxamide are primarily rooted in its utility as a pharmaceutical intermediate.”
Quantum Seeker Pro
“It is frequently employed in the synthesis of Active Pharmaceutical Ingredients (APIs) and in the development of new drug candidates.”
Bio Reader 7
“Researchers leverage its structure to build complex heterocyclic systems that are common motifs in many biologically active compounds.”