The Chemistry Behind 2-Amino-3-bromopyridine: A Versatile Organic Synthesis Building Block
Organic synthesis is the art and science of constructing complex molecules from simpler precursors. At the heart of this field are versatile building blocks, compounds that possess the right combination of functional groups and reactivity to enable the creation of diverse molecular structures. 2-Amino-3-bromopyridine (CAS: 13534-99-1) exemplifies such a building block, offering chemists a powerful tool for innovation. As a dedicated manufacturer of fine chemicals in China, we are committed to providing researchers and industrial chemists with high-quality 2-Amino-3-bromopyridine to fuel their synthetic endeavors.
The molecular structure of 2-Amino-3-bromopyridine is key to its synthetic utility. It features a pyridine core, a six-membered aromatic ring containing a nitrogen atom, which is a common motif in many pharmaceuticals and biologically active compounds. Attached to this ring are two crucial functional groups: an amino group (-NH2) at the 2-position and a bromine atom (-Br) at the 3-position. The amino group can participate in a wide range of reactions, including acylation, alkylation, and diazotization. The bromine atom, being a good leaving group, is ideal for various cross-coupling reactions, such as Suzuki, Sonogashira, and Buchwald-Hartwig couplings, which are indispensable in modern organic synthesis for forming carbon-carbon and carbon-heteroatom bonds.
Chemists looking to buy 2-Amino-3-bromopyridine for their projects can leverage its reactivity to introduce complex substituents onto the pyridine ring or to link it to other molecular fragments. This makes it an exceptionally valuable intermediate for creating drug candidates, advanced materials, and specialized organic molecules. For instance, researchers can utilize palladium-catalyzed cross-coupling reactions with boronic acids or organostannanes to build elaborate biaryl systems or alkynyl-substituted pyridines, respectively. The ability to perform these reactions with high efficiency and selectivity is a testament to the compound's design and purity.
Our role as a manufacturer in China is to ensure that this crucial building block is available with consistent high purity (often 97% min.) and at competitive prices. This allows research institutions and chemical companies to purchase the quantities they need for both small-scale laboratory experiments and larger industrial syntheses. We understand the importance of reliable access to such reagents for driving innovation in organic chemistry. We also offer opportunities to inquire about price for bulk orders and to request free samples, facilitating their evaluation in various synthetic schemes.
In summary, 2-Amino-3-bromopyridine is more than just a chemical compound; it is a gateway to creating novel molecular architectures. Its strategic functionalization and the established synthetic methodologies it participates in make it a cornerstone for many organic synthesis projects. We invite you to partner with us, a trusted China supplier, to acquire this essential building block and unlock new possibilities in your chemical research and development.
Perspectives & Insights
Nano Explorer 01
“Attached to this ring are two crucial functional groups: an amino group (-NH2) at the 2-position and a bromine atom (-Br) at the 3-position.”
Data Catalyst One
“The amino group can participate in a wide range of reactions, including acylation, alkylation, and diazotization.”
Chem Thinker Labs
“The bromine atom, being a good leaving group, is ideal for various cross-coupling reactions, such as Suzuki, Sonogashira, and Buchwald-Hartwig couplings, which are indispensable in modern organic synthesis for forming carbon-carbon and carbon-heteroatom bonds.”