Ethyl Azidoacetate (CAS 637-81-0) is a chemical compound that has garnered significant attention in various scientific disciplines due to its unique molecular structure and versatile reactivity. Understanding its chemical properties and handling requirements is crucial for researchers, chemists, and procurement specialists to ensure both effective utilization and safe laboratory practices. As a leading supplier of this vital intermediate, we aim to provide comprehensive information.

Chemically, Ethyl Azidoacetate is an organic ester featuring an azide functional group (-N3). Its molecular formula is C4H7N3O2, with a molecular weight of approximately 129.12 g/mol. The presence of the azide group makes it highly susceptible to undergo various chemical reactions. Most notably, it is a key participant in 1,3-dipolar cycloaddition reactions, particularly the copper-catalyzed azide-alkyne cycloaddition (CuAAC), often termed 'click chemistry'. This reaction leads to the formation of stable triazole rings, a common motif in pharmaceuticals and advanced materials. The ester portion of the molecule also offers avenues for further chemical modification, such as hydrolysis or transesterification, increasing its synthetic utility.

The physical properties of Ethyl Azidoacetate are also important for handling and storage. It is typically described as a colorless to light yellow liquid. Its density is reported to be around 1.11-1.127 g/mL at 25°C, and its boiling point is approximately 44-46°C at 2 mmHg, or a higher reported value of 164°C under unspecified conditions. For effective use, it is often stored under refrigerated conditions (e.g., +4°C) to maintain stability, protected from light and moisture. As a chemical intermediate, its purity, often guaranteed at ≥95% or ≥99% GC, is critical for successful synthesis outcomes.

When it comes to safety, Ethyl Azidoacetate, like many azide compounds, requires careful handling. It is classified as a hazardous material and may be sensitive to heat, shock, or friction. Standard laboratory safety protocols, including the use of personal protective equipment (PPE) such as gloves, eye protection, and lab coats, are mandatory. It's advisable to work with it in a well-ventilated area, preferably a fume hood. Material Safety Data Sheets (MSDS) or Safety Data Sheets (SDS) provide detailed hazard information, handling instructions, and emergency procedures, which should always be consulted before use. For procurement managers, ensuring that their chosen Ethyl Azidoacetate manufacturer provides comprehensive safety documentation is vital.

For those seeking to buy Ethyl Azidoacetate, understanding its chemical behavior and safety profile is as important as knowing its applications. Whether you are a researcher in organic synthesis, pharmaceutical development, or material science, partnering with a reputable Ethyl Azidoacetate supplier like us ensures access to high-quality, well-characterized chemical products. We are committed to providing reliable information and dependable products to support your scientific endeavors. Reach out to us for detailed specifications, safety data, and quotes for your Ethyl Azidoacetate needs.