N-Hydroxyethyl Piperidine (CAS 3040-44-6) is a fascinating molecule with a well-defined chemical structure that dictates its utility as a key intermediate. Understanding its synthesis and inherent properties is crucial for chemists and procurement specialists who rely on this compound for their manufacturing processes. As a dedicated N-Hydroxyethyl Piperidine manufacturer China, we possess deep insights into its chemical intricacies.

Synthesis Pathways for N-Hydroxyethyl Piperidine

The synthesis of N-Hydroxyethyl Piperidine typically involves the reaction of piperidine with ethylene oxide. This nucleophilic ring-opening reaction is a common and efficient method for introducing the hydroxyethyl group onto the nitrogen atom of the piperidine ring. Alternative methods might involve the reaction of piperidine with 2-chloroethanol under basic conditions. The efficiency and purity of the final product are heavily dependent on reaction conditions, catalyst selection, and subsequent purification techniques. Our manufacturing processes are optimized to ensure high yields and superior purity, often achieving ≥99% assay, when you buy N-Hydroxyethyl Piperidine CAS 3040-44-6 from us.

Key Chemical Properties and Their Implications

The molecular formula of N-Hydroxyethyl Piperidine is C7H15NO, with a molecular weight of approximately 129.2 g/mol. At room temperature, it typically presents as a slightly brown or colorless liquid. Its density is around 0.970–0.975 g/cm³, and it has a relatively low water content (≤0.3%). The boiling point is generally in the range of 199-202°C. The presence of both a tertiary amine (piperidine nitrogen) and a primary alcohol group makes N-Hydroxyethyl Piperidine a bifunctional molecule, capable of undergoing reactions characteristic of both functional groups.

These properties make it an excellent intermediate for:

  • Esterification and Etherification: The hydroxyl group can be readily esterified or etherified to create new functional derivatives.
  • Amine Reactions: The tertiary amine can act as a nucleophile, a base, or be quaternized.
  • Hydrogen Bonding: The hydroxyl group allows for hydrogen bonding, influencing its solubility and physical properties.

This chemical versatility is what makes it so valuable as a building block in complex synthesis. For those seeking a reliable N-Hydroxyethyl Piperidine supplier, understanding these chemical traits helps in appreciating the compound's role in their specific applications.

Applications Driven by Chemistry

The properties discussed directly translate into its primary applications as a pharmaceutical intermediate, in organic synthesis, and within the petrochemical sector. Its ability to form salts, undergo derivatization, and participate in a variety of reactions makes it indispensable. When you consider the N-Hydroxyethyl Piperidine price, remember that it reflects the complexity and precision involved in its synthesis and purification to meet these demanding chemical requirements.

By partnering with an experienced manufacturer that understands the deep chemistry behind N-Hydroxyethyl Piperidine, you ensure access to a product that consistently meets your specifications and drives innovation in your field.