Rotigotine, a non-ergoline dopamine agonist, has been a significant therapeutic option for managing Parkinson's disease and restless legs syndrome. Its efficacy stems from its ability to stimulate dopamine receptors in the brain, alleviating motor and non-motor symptoms. The synthesis of such a complex molecule requires a series of precise chemical transformations, relying on high-quality pharmaceutical intermediates as building blocks.

One of the most critical intermediates in the synthesis of Rotigotine is (S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine hydrochloride, identified by its CAS number 93601-86-6. This chiral compound provides the core tetralin structure and the necessary amine functionality, with the specific (S)-stereochemistry being crucial for the pharmacological activity of the final drug. The synthesis pathway often involves coupling this intermediate with other functional groups to construct the complete Rotigotine molecule.

For manufacturers and researchers in the pharmaceutical industry, securing a reliable source of high-purity (S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine hydrochloride is paramount. Impurities or incorrect stereoisomers can lead to significant challenges in downstream synthesis, potentially resulting in reduced yields, the formation of unwanted byproducts, and issues with regulatory compliance. Therefore, a supplier's commitment to quality, evident in purity specifications (often ≥99%) and stringent quality control, is a key factor when deciding where to buy this intermediate.

NINGBO INNO PHARMCHEM CO.,LTD. plays a vital role in this supply chain. As a dedicated manufacturer and supplier, we produce CAS 93601-86-6 with the high standards required for pharmaceutical synthesis. We understand that reliable access to this key intermediate is essential for companies involved in Rotigotine production or research into similar dopaminergic agents. Our capacity to produce this compound in various quantities, from research samples to bulk industrial supply, ensures that our clients can maintain uninterrupted development and manufacturing schedules.

The development of effective pharmaceuticals like Rotigotine is a testament to the advancements in organic chemistry and the availability of sophisticated intermediates. We are proud to contribute to this field by offering a consistent and high-quality supply of essential building blocks. For any inquiries regarding the purchase of (S)-1,2,3,4-Tetrahydro-5-methoxy-N-propyl-2-naphthalenamine hydrochloride or other fine chemicals, please reach out to NINGBO INNO PHARMCHEM CO.,LTD. We are your trusted partner in pharmaceutical synthesis.