For chemists and researchers, understanding the fundamental properties of chemical compounds is key to unlocking their potential. 1,1-Cyclohexane Diacetic Anhydride, identified by its CAS number 1010-26-0, is one such compound that holds significant value in the realm of organic synthesis and pharmaceutical intermediate production. This article delves into the chemical characteristics of this anhydride and explores its critical applications, providing valuable insights for industry professionals seeking to purchase or utilize this versatile molecule.

The molecular structure of 1,1-Cyclohexane Diacetic Anhydride features a cyclohexane ring fused with a cyclic anhydride moiety. This unique arrangement contributes to its specific chemical reactivity. Physically, it is often described as a white to light yellow powder or crystalline solid, with reported melting points typically in the range of 67-70 °C. Its boiling point is noted at approximately 126 °C at 0.5 mmHg, indicating its thermal stability under specific conditions. The presence of the anhydride group makes it susceptible to nucleophilic attack, readily undergoing reactions like hydrolysis to form the corresponding diacid or aminolysis to form amides. This reactivity profile is precisely why it serves as an effective intermediate in complex chemical syntheses.

The primary application driving the demand for 1,1-Cyclohexane Diacetic Anhydride is its role as a precursor in the synthesis of gabapentin. Gabapentin is a widely used pharmaceutical agent, and the efficient synthesis of this drug relies heavily on the availability of high-quality intermediates like this anhydride. The reaction typically involves the anhydride reacting with an amine to form the desired amide structure, a critical step in constructing the gabapentin molecule. For companies involved in generic drug manufacturing or the development of new pharmaceutical compounds, sourcing this intermediate from reliable chemical suppliers in China is a common and effective strategy.

Beyond pharmaceuticals, 1,1-Cyclohexane Diacetic Anhydride can also find applications in the synthesis of specialty polymers, fine chemicals, and advanced materials. Its cyclic nature and reactive anhydride function allow for its incorporation into various polymer backbones or as a cross-linking agent. For researchers exploring novel chemical compounds, this anhydride offers a valuable starting point for building complex molecular architectures. When considering purchase options, focusing on manufacturers that can guarantee consistent purity and reliable supply is paramount for successful research and development outcomes.

In summary, 1,1-Cyclohexane Diacetic Anhydride is a compound of considerable importance in modern chemistry. Its well-defined chemical properties and its critical role as a pharmaceutical intermediate, particularly for gabapentin synthesis, make it a sought-after material. For professionals in the chemical industry, understanding these aspects and identifying reliable suppliers for purchasing this anhydride is essential for driving innovation and ensuring efficient production processes. If your work requires this chemical, engaging with reputable manufacturers and suppliers will provide the quality and consistency you need.