2-Pyridinemethanol, identified by its CAS number 586-98-1, is a fascinating molecule with significant utility in both the pharmaceutical and broader chemical industries. As a light yellow liquid, its defining characteristic is the presence of both a pyridine ring and a hydroxymethyl group, a combination that makes it a versatile synthon for organic chemists.

The chemical properties of 2-Pyridinemethanol are well-documented. Its boiling point of approximately 222.6 °C at 760 mmHg and a melting point of 5 °C place it firmly in the liquid state under standard laboratory conditions. The molecular formula C6H7NO and a molecular weight of 109.126 further define its chemical identity. The flash point of 81.7 °C indicates its flammability characteristics, which are important considerations for safe handling and storage, typically in cool, ventilated areas.

In terms of synthesis, while the article mentions its application as an intermediate, detailed synthetic pathways for 2-Pyridinemethanol itself often involve the reduction of pyridine-2-carboxylic acid or its esters, or the hydrolysis of 2-(halomethyl)pyridines. The availability of reliable synthetic methods is crucial for ensuring a consistent supply for its downstream applications.

The most prominent application of 2-Pyridinemethanol lies in its role as a key intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs). Its structure is particularly well-suited for incorporation into complex molecular architectures, such as the aforementioned Neratinib. This means that understanding its reactivity, such as the alcohol group's potential for esterification, etherification, or oxidation, and the pyridine nitrogen's ability to act as a ligand or base, is vital for medicinal chemists.

For businesses looking to buy 2-Pyridinemethanol, it's essential to partner with a reputable manufacturer or supplier. Companies specializing in fine chemicals and pharmaceutical intermediates, such as ourselves, ensure the product meets the required specifications, including the typical ≥98.0% assay. This focus on purity is what makes 2-Pyridinemethanol a reliable building block for the pharmaceutical industry, enabling the development of innovative treatments.

Exploring the chemistry of 2-Pyridinemethanol opens up avenues for new synthetic strategies and the discovery of novel compounds. Whether you are a researcher seeking a specific chemical building block or a procurement manager ensuring the continuity of your supply chain, understanding the intrinsic properties and applications of this vital intermediate is key. If you're in need of this chemical, consider reaching out to us for your sourcing requirements.