At NINGBO INNO PHARMCHEM CO.,LTD., we are passionate about the chemistry that drives innovation. 4-Bromobenzenesulfonamide (CAS 701-34-8) is a compound that exemplifies the versatility and utility of well-designed chemical intermediates. Understanding its chemical properties and potential synthesis pathways is key for chemists seeking to leverage its capabilities in their research and development efforts.

4-Bromobenzenesulfonamide, with the molecular formula C6H6BrNO2S, is characterized by a benzene ring substituted with a bromine atom at the para position relative to the sulfonamide group (-SO2NH2). This structure imparts specific reactivity. The bromine atom is an excellent leaving group in nucleophilic aromatic substitution reactions and is highly reactive in palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura, Heck, and Sonogashira couplings. These reactions are foundational in modern organic synthesis, allowing for the formation of complex carbon-carbon bonds.

The sulfonamide moiety itself is also chemically versatile. It can participate in N-alkylation or N-acylation reactions to introduce further complexity. The acidic nature of the N-H proton can also be exploited in certain catalytic cycles. The high purity standard of 98% for 4-Bromobenzenesulfonamide, which NINGBO INNO PHARMCHEM CO.,LTD. ensures, is critical for the success of these reactions, minimizing side products and improving yields.

While the direct synthesis methods can vary, a common approach involves the chlorosulfonation of bromobenzene followed by amination. Alternatively, bromination of benzenesulfonamide can also yield the desired product. For industrial applications, efficiency, cost-effectiveness, and environmental considerations are paramount in selecting a synthesis route. When you choose to buy 4-bromobenzenesulfonamide, you are selecting a meticulously produced intermediate.

As a leading supplier, NINGBO INNO PHARMCHEM CO.,LTD. provides high-quality 4-Bromobenzenesulfonamide, ensuring that researchers and industries have access to this indispensable building block. The competitive price and adherence to strict quality standards make us a preferred partner for those engaged in demanding organic synthesis and pharmaceutical intermediate applications.