1,1'-Bi-2-naphthol, widely recognized by its acronym BINOL (CAS No. 602-09-5), is a compound of significant interest in organic chemistry due to its unique structural and chiral properties. As a manufacturer, understanding its synthesis and properties is fundamental to providing this essential chemical to the global market. This article delves into the chemistry of BINOL and its availability.

The synthesis of BINOL typically begins with the oxidative coupling of 2-naphthol. Various catalytic systems, often involving copper salts or iron complexes, are employed to achieve this dimerization. The process requires careful control of reaction conditions, including temperature, solvent, and catalyst selection, to maximize yield and purity. Developing efficient and scalable synthesis routes is a key focus for manufacturers like ourselves, ensuring a consistent supply of high-quality BINOL. We maintain rigorous quality control throughout our manufacturing process, guaranteeing a minimum purity of 97%.

BINOL exists as a pair of enantiomers, (R)-BINOL and (S)-BINOL, and also as a racemic mixture. This chirality is the foundation of its utility in asymmetric synthesis. The compound typically appears as a white to light yellow or beige powder, with a melting point around 215-218°C. Its solubility in common organic solvents like dioxane and toluene further aids its application in various reaction media. Understanding these properties is vital for researchers and manufacturers who plan to buy BINOL for specific applications.

The applications of BINOL are extensive, primarily as a chiral ligand in catalysis. It is used to create effective catalysts for a wide range of asymmetric transformations, including Diels-Alder reactions, Michael additions, and various metal-catalyzed coupling reactions. Furthermore, BINOL serves as a crucial intermediate in the synthesis of advanced materials and complex pharmaceutical compounds where stereochemistry is critical. The global demand for BINOL underscores its importance across multiple industries.

For those looking to purchase BINOL, it is important to partner with a reliable supplier. We, as a leading BINOL manufacturer, ensure global availability and competitive pricing. Our commitment to quality and consistent production makes us an ideal choice for companies requiring this vital chemical intermediate. Whether for laboratory research or industrial-scale production, our ability to supply high-purity BINOL reliably supports your chemical endeavors. Contact us today to learn more about our BINOL products and how we can meet your sourcing needs.