Chirality, the property of non-superimposable mirror images, is a fundamental concept in chemistry, particularly in the fields of pharmaceuticals, agrochemicals, and materials science. The ability to synthesize specific enantiomers with high purity is often the key to unlocking desired biological activity or material properties. Within this domain, (R)-(+)-1,1'-Bi-2-naphthol, identified by CAS number 18531-94-7, stands out as a highly effective and versatile chiral building block and ligand. As a leading supplier from China, we provide this essential chemical for your advanced synthetic needs.

The chemical profile of (R)-(+)-1,1'-Bi-2-naphthol is characterized by its white to off-white powder form and its solubility in organic solvents like dioxane and THF, while being insoluble in water. Its melting point typically ranges between 215-218 °C, indicating a stable solid structure. The compound's defining feature is its optical activity, represented by a specific rotation ([α]21/D +34°, c = 1 in THF), which is crucial for its function in asymmetric synthesis. For professionals in R&D, understanding these properties is vital when considering how to best utilize this compound in their processes. Purchasing from a reputable manufacturer ensures that these specifications are consistently met.

The primary application of (R)-BINOL lies in its role as a chiral ligand in transition metal-catalyzed asymmetric reactions. It forms highly effective chiral catalytic complexes that can direct a wide array of transformations enantioselectively. This includes crucial reactions such as asymmetric hydrogenations, C-C bond formations (like Michael additions and aldol reactions), and C-N bond formations. Its utility extends to the synthesis of complex natural products and the development of novel APIs, where precise stereochemical control is paramount. The availability of high-quality (R)-(+)-1,1'-Bi-2-naphthol from Chinese manufacturers at competitive prices makes advanced chiral synthesis more accessible.

For businesses looking to buy this critical intermediate, engaging with a knowledgeable supplier is beneficial. We, as an established manufacturer and supplier of fine chemicals in China, offer (R)-(+)-1,1'-Bi-2-naphthol with guaranteed purity and optical activity. Our production processes are optimized to deliver consistent quality, supporting your critical applications. Whether for research-scale experiments or industrial production, our reliable supply chain and commitment to excellence make us your ideal partner for this essential chiral molecule.