For research and development scientists pushing the boundaries of chemical innovation, understanding the fundamental properties and synthetic potential of key reagents is paramount. 2-Amino-4-methylbenzoic acid (CAS 2305-36-4) is one such molecule, offering a rich platform for diverse chemical transformations. This article explores its chemical characteristics and highlights its significant role as a versatile building block.

Deconstructing the Molecule: Chemical Properties of 2-Amino-4-methylbenzoic Acid

At its core, 2-Amino-4-methylbenzoic acid is an ortho-substituted benzoic acid derivative. Its structure comprises:

  • An Aromatic Ring: Providing a stable scaffold for further functionalization.
  • An Amino Group (-NH2): Positioned ortho to the carboxylic acid, this group is nucleophilic and can participate in amidation, diazotization, and other reactions characteristic of anilines.
  • A Carboxylic Acid Group (-COOH): This acidic functional group can undergo esterification, salt formation, and decarboxylation under specific conditions. Its proximity to the amino group can influence reactivity through intramolecular interactions.
  • A Methyl Group (-CH3): Located para to the amino group, this electron-donating substituent subtly influences the electronic distribution of the aromatic ring, affecting reactivity.

These functional groups, combined with the methyl substituent, result in a molecule with a melting point of approximately 160°C and a molecular formula of C8H9NO2. Its solubility in common organic solvents like DMSO and methanol, albeit slightly, is an important consideration for reaction design. The pKa value, around 5.11, indicates its acidic nature.

Synthetic Utility: A Foundation for Advanced Molecules

The unique arrangement of functional groups in 2-Amino-4-methylbenzoic acid makes it an ideal starting material or intermediate for a wide array of synthetic pathways:

  • Pharmaceutical Synthesis: R&D scientists often leverage this compound to construct heterocyclic ring systems or introduce specific functionalities into drug candidates. Its potential biological activity, explored in medicinal chemistry, further enhances its value. If you are looking to buy specific pharmaceutical intermediates, this is a prime candidate.
  • Agrochemical Development: The molecule's structure lends itself to modifications that can yield potent herbicides or plant growth regulators. Research into new agrochemical formulations frequently involves such versatile building blocks.
  • Color Chemistry: As a precursor for dyes, its ability to be diazotized and coupled makes it a valuable component in the synthesis of azo dyes.
  • Catalysis and Materials Science: Researchers may explore its derivatives for applications in catalysis or as monomers for specialty polymers.

Procurement for Research and Development

For R&D scientists, reliable access to high-quality 2-Amino-4-methylbenzoic acid is crucial for reproducible results. When you need to purchase this compound, look for a supplier that can provide:

  • High Purity: Essential for unambiguous experimental outcomes and avoiding side reactions.
  • Detailed Specifications: Access to CoA and structural information ensures you are using the correct material.
  • Small-to-Medium Quantities: Availability in research-friendly sizes facilitates laboratory work.
  • Prompt Delivery: Timely arrival of materials keeps research projects on schedule.

We understand the critical role of intermediates like 2-Amino-4-methylbenzoic acid (CAS 2305-36-4) in driving scientific discovery. As a leading manufacturer and supplier, we are committed to providing researchers with the quality materials they need. Contact us to obtain a sample or request a quote and elevate your next synthesis project.