In the realm of organic chemistry, certain molecular structures offer unique functionalities that drive innovation across industries. Pyrogallol-4-carboxaldehyde, more commonly known as 2,3,4-Trihydroxybenzaldehyde (CAS 2144-08-3), is one such compound. Its distinct arrangement of hydroxyl groups and an aldehyde function on a benzene ring confers it with remarkable chemical reactivity and versatility. This article explores its key chemical properties and highlights why it is an indispensable intermediate for many industrial applications, particularly for those looking to buy from a reliable manufacturer.

Decoding the Chemical Properties

The chemical identity of 2,3,4-Trihydroxybenzaldehyde is defined by its molecular formula, C7H6O4, and a molecular weight of 154.12 g/mol. Its most striking feature is the presence of three hydroxyl (-OH) groups and one aldehyde (-CHO) group attached to the aromatic ring. This phenolic aldehyde structure imbues the molecule with several key properties:

  • Reactivity of Hydroxyl Groups: The phenolic hydroxyls contribute to its antioxidant capabilities and make it susceptible to oxidation under certain conditions. They also allow for reactions such as etherification and esterification, expanding its synthetic utility.
  • Reactivity of Aldehyde Group: The aldehyde moiety is a versatile functional group, capable of undergoing nucleophilic addition reactions, oxidation to carboxylic acids, and reduction to primary alcohols. It readily forms Schiff bases with amines, a crucial step in many synthetic pathways.
  • Solubility: While sparingly soluble in water (approximately 1.541 g/L at 25°C), it shows better solubility in polar organic solvents like DMSO and methanol, which is important for reaction medium selection.
  • Physical State: Typically appearing as a white to off-white crystalline powder, its physical form is an indicator of its purity and handling characteristics.

Industrial Significance and Applications

The industrial significance of 2,3,4-Trihydroxybenzaldehyde stems directly from its chemical properties, enabling its use in:

  • Pharmaceutical Intermediates: It is a vital precursor in the synthesis of various APIs, especially those aimed at antioxidant, anti-inflammatory, and antimicrobial effects.
  • Cosmetic Formulations: Its antioxidant nature makes it a valuable ingredient in skincare products designed for protection and anti-aging.
  • Fine Chemical Synthesis: It serves as a versatile building block for creating more complex organic molecules used in dyes, flavors, and other specialty chemicals.

Partnering with a Trusted Supplier

For businesses that need to reliably purchase high-purity CAS 2144-08-3, partnering with an established supplier in China is often the most effective strategy. We pride ourselves on being a dedicated manufacturer of organic intermediates, ensuring that our products meet rigorous quality standards. We offer competitive prices and dependable supply to support your ongoing projects. Reach out to us for a quotation and experience the benefits of sourcing from a quality-focused provider.