The Critical Role of 1,3-Dichloro-5-fluorobenzene in Pharmaceutical Intermediate Synthesis
The synthesis of pharmaceuticals is a complex, multi-step process that relies heavily on the quality and availability of chemical intermediates. Among these vital components, 1,3-Dichloro-5-fluorobenzene has emerged as a compound of significant importance. NINGBO INNO PHARMCHEM CO.,LTD. actively utilizes this halogenated aromatic compound, recognizing its indispensable role in the production of advanced pharmaceutical intermediates and, consequently, novel drug therapies.
1,3-Dichloro-5-fluorobenzene, cataloged under CAS number 1435-46-7, is characterized by its molecular formula C6H3Cl2F and a molecular weight of 164.99200 g/mol. It typically appears as a colorless to pale yellow liquid, possessing a density of 1.403 g/cm3 and a boiling point of 68°C. These physical and chemical properties are carefully considered by chemists at NINGBO INNO PHARMCHEM CO.,LTD. during the design and execution of synthetic routes. The stated purity of ≥99.0% ensures that the compound functions reliably in complex chemical transformations, a non-negotiable aspect in pharmaceutical manufacturing.
The primary application for 1,3-dichloro-5-fluorobenzene lies in its function as a pharmaceutical intermediate. Its molecular structure, featuring both chlorine and fluorine substituents on a benzene ring, provides specific points of reactivity that are highly sought after in medicinal chemistry. This allows for the efficient construction of complex molecular scaffolds that are foundational to many active pharmaceutical ingredients (APIs). NINGBO INNO PHARMCHEM CO.,LTD. employs this intermediate to build intricate molecular architectures, ultimately contributing to the development of new medicines.
The strategic use of 1,3-dichloro-5-fluorobenzene in organic synthesis is a cornerstone of modern drug development. Researchers and manufacturers rely on such well-defined intermediates to ensure reproducible results and efficient production cycles. The compound's handling and storage recommendations—kept in tightly closed containers in cool, dry, and well-ventilated areas—are standard practices at NINGBO INNO PHARMCHEM CO.,LTD. to maintain its quality. As the pharmaceutical industry continues to push the boundaries of drug discovery, the demand for high-quality, precisely synthesized intermediates like 1,3-dichloro-5-fluorobenzene remains exceptionally high.
In summary, 1,3-dichloro-5-fluorobenzene is more than just a chemical; it is a critical enabler of pharmaceutical innovation, facilitating the synthesis of life-changing treatments.
Perspectives & Insights
Chem Catalyst Pro
“Researchers and manufacturers rely on such well-defined intermediates to ensure reproducible results and efficient production cycles.”
Agile Thinker 7
“The compound's handling and storage recommendations—kept in tightly closed containers in cool, dry, and well-ventilated areas—are standard practices at NINGBO INNO PHARMCHEM CO.”
Logic Spark 24
“As the pharmaceutical industry continues to push the boundaries of drug discovery, the demand for high-quality, precisely synthesized intermediates like 1,3-dichloro-5-fluorobenzene remains exceptionally high.”