The Critical Role of 5-Chloro-2-Thiophenecarboxylic Acid in Modern Pharmaceutical Manufacturing
In the intricate world of pharmaceutical manufacturing, the quality and reliability of raw materials and intermediates are paramount. Among these crucial components, 5-Chloro-2-thiophenecarboxylic acid (CAS No.: 24065-33-6) stands out as a pivotal compound. Its primary significance lies in its role as a key intermediate in the synthesis of Rivaroxaban, a widely prescribed anticoagulant that plays a vital role in preventing and treating serious conditions like deep vein thrombosis and pulmonary embolism. As a leading supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-purity 5-Chloro-2-thiophenecarboxylic acid that meets the stringent demands of the pharmaceutical sector.
The chemical structure of 5-Chloro-2-thiophenecarboxylic acid, featuring a thiophene ring with a chlorine atom and a carboxylic acid group, makes it an indispensable building block in complex organic synthesis pathways. Its physical characteristics, such as a white to yellowish crystalline powder appearance and a melting point typically between 154-158 °C, are indicative of its stable nature, facilitating its handling and use in industrial processes. The compound's assay purity, often exceeding 97.0%, is a critical factor ensuring the quality of downstream pharmaceutical products.
The demand for effective anticoagulants like Rivaroxaban continues to grow globally, driven by an aging population and an increased prevalence of cardiovascular diseases. This growing demand directly translates to a consistent need for high-quality intermediates like 5-Chloro-2-thiophenecarboxylic acid. Manufacturers and suppliers in China, such as NINGBO INNO PHARMCHEM CO.,LTD., play a crucial role in meeting this global demand by leveraging advanced synthesis techniques and robust quality control measures. By choosing a reliable 5-Chloro-2-thiophenecarboxylic acid manufacturer in China, pharmaceutical companies can ensure a consistent and high-quality supply, which is essential for uninterrupted production and patient care.
Beyond its established role in Rivaroxaban synthesis, the inherent chemical properties of 5-Chloro-2-thiophenecarboxylic acid suggest potential for broader applications in organic synthesis and the development of new bioactive molecules. Researchers are continually exploring novel thiophene derivatives for therapeutic advancements, further solidifying the importance of this intermediate in the ongoing evolution of the pharmaceutical landscape. NINGBO INNO PHARMCHEM CO.,LTD. remains committed to innovation and quality, striving to be a premier supplier for this critical chemical intermediate, supporting the development of next-generation pharmaceuticals.
Perspectives & Insights
Alpha Spark Labs
“Its physical characteristics, such as a white to yellowish crystalline powder appearance and a melting point typically between 154-158 °C, are indicative of its stable nature, facilitating its handling and use in industrial processes.”
Future Pioneer 88
“0%, is a critical factor ensuring the quality of downstream pharmaceutical products.”
Core Explorer Pro
“The demand for effective anticoagulants like Rivaroxaban continues to grow globally, driven by an aging population and an increased prevalence of cardiovascular diseases.”