The Crucial Role of 2,4-Diamino-6-hydroxypyrimidine in Pharma Synthesis
In the dynamic landscape of pharmaceutical research and development, the quality and availability of key chemical intermediates are paramount. Among these, 2,4-Diamino-6-hydroxypyrimidine, identified by its CAS number 56-06-4, stands out as a critical building block. This compound's significance stems from its specific biological activity and its utility in complex organic synthesis, making it a sought-after material for B2B procurement professionals and R&D scientists.
At the core of 2,4-Diamino-6-hydroxypyrimidine's value is its function as a potent and selective inhibitor of GTP cyclohydrolase I (GCHI). This enzyme plays a rate-limiting role in the de novo synthesis of tetrahydrobiopterin (BH4), a vital cofactor involved in numerous biological processes. Furthermore, BH4 is essential for the activity of nitric oxide synthases (NOS), enzymes responsible for producing nitric oxide (NO), a crucial signaling molecule in the cardiovascular and nervous systems. By inhibiting GCHI, 2,4-Diamino-6-hydroxypyrimidine effectively modulates BH4 levels and, consequently, NO production. This characteristic makes it an invaluable tool for researchers investigating conditions related to NO deficiency or dysregulation.
For pharmaceutical companies and research institutions, the ability to reliably buy high-purity 2,4-Diamino-6-hydroxypyrimidine (CAS 56-06-4) is essential. As a leading manufacturer and supplier based in China, we understand the stringent requirements of the pharmaceutical industry. Our commitment is to provide material with a minimum purity of 97%, ensuring consistent and reproducible results in your synthetic pathways. Whether you are developing novel therapeutics for neurological disorders, cardiovascular diseases, or inflammatory conditions, the availability of this intermediate directly impacts your project's success.
Procurement professionals seeking to optimize their supply chain will find significant advantages in sourcing from established manufacturers. Understanding the price and availability of intermediates like 2,4-Diamino-6-hydroxypyrimidine is crucial for budgeting and project planning. We offer competitive pricing and transparent quotes, particularly for bulk orders, making it easier for organizations to secure large quantities required for scale-up and commercial production. The logistical advantages of sourcing from a dedicated supplier in China can also translate to reduced lead times and enhanced supply chain resilience.
The application of 2,4-Diamino-6-hydroxypyrimidine extends beyond its direct use as a research compound. It serves as a key intermediate in the synthesis of more complex pharmaceutical agents. Its pyrimidine core offers a versatile scaffold for chemists to build upon, leading to the development of drug candidates with tailored pharmacological profiles. When considering the purchase of such a critical component, partnering with a reputable manufacturer that offers strong technical support and a robust quality assurance system is a strategic decision. We aim to be that partner, facilitating innovation in drug discovery and development through reliable access to essential chemical building blocks.
Perspectives & Insights
Core Pioneer 24
“This enzyme plays a rate-limiting role in the de novo synthesis of tetrahydrobiopterin (BH4), a vital cofactor involved in numerous biological processes.”
Silicon Explorer X
“Furthermore, BH4 is essential for the activity of nitric oxide synthases (NOS), enzymes responsible for producing nitric oxide (NO), a crucial signaling molecule in the cardiovascular and nervous systems.”
Quantum Catalyst AI
“By inhibiting GCHI, 2,4-Diamino-6-hydroxypyrimidine effectively modulates BH4 levels and, consequently, NO production.”