In the complex landscape of pharmaceutical manufacturing, the quality and availability of key intermediates are paramount. One such compound, 2-Aminobenzenethiol (CAS: 137-07-5), stands out for its indispensable role in the synthesis of various active pharmaceutical ingredients (APIs). Understanding its properties, applications, and reliable sourcing channels is crucial for procurement managers and R&D scientists in the pharmaceutical sector.

2-Aminobenzenethiol, also known by synonyms such as o-aminothiophenol or 2-mercaptoaniline, is a bifunctional molecule containing both an amine (-NH2) and a thiol (-SH) group attached to a benzene ring. This unique structure imbues it with remarkable reactivity, making it a preferred building block for a wide array of organic syntheses. Its CAS number, 137-07-5, uniquely identifies this critical compound within global chemical inventories.

One of the most notable applications of 2-Aminobenzenethiol is in the synthesis of Diltiazem (CAS: 42399-41-7), a widely used calcium channel blocker primarily prescribed for managing hypertension, angina, and certain heart arrhythmias. The efficient and high-purity production of Diltiazem relies heavily on the quality of the 2-Aminobenzenethiol used as a starting material. Pharmaceutical companies seeking to buy this intermediate often prioritize suppliers who can guarantee consistent purity levels, typically above 98.0%, to ensure the efficacy and safety of the final drug product.

Beyond Diltiazem, 2-Aminobenzenethiol serves as a foundational element in creating other pharmaceutical intermediates and complex heterocyclic compounds. Its ability to readily cyclize into benzothiazoles, for instance, opens doors to novel drug discovery and development pipelines. For R&D scientists exploring new therapeutic agents, having access to a dependable supplier of 2-Aminobenzenethiol is essential for iterative synthesis and scale-up studies.

For procurement professionals tasked with sourcing these vital chemicals, identifying a reputable manufacturer and supplier in China or globally is a key strategic decision. Factors such as guaranteed purity, competitive pricing, stable supply chain, and adherence to international regulatory standards (e.g., REACH, TSCA) are critical. Companies looking to buy 2-Aminobenzenethiol should engage with manufacturers who can provide comprehensive technical data sheets and certificates of analysis, ensuring the material meets all specified requirements.

The market for 2-Aminobenzenethiol is robust, driven by the ever-growing demand for pharmaceuticals worldwide. Innovations in synthesis methods, including greener chemistry approaches, are also shaping the production and availability of this intermediate. As the pharmaceutical industry continues to expand, the role of 2-Aminobenzenethiol as a cornerstone intermediate will only become more pronounced. We invite you to explore our offerings for high-purity 2-Aminobenzenethiol, ensuring your pharmaceutical manufacturing processes are supported by the finest raw materials available from a trusted supplier.