In the intricate world of pharmaceutical research and development, the demand for specialized chemical building blocks is ever-increasing. Among these, unnatural amino acids have emerged as pivotal components, enabling the creation of novel therapeutics with enhanced efficacy and specificity. One such vital compound is 2-Aminoisobutyric Acid (2-AIB), a non-proteinogenic amino acid that plays a significant role in advancing drug discovery and peptide synthesis. As a dedicated manufacturer and supplier of high-quality pharmaceutical intermediates, we are proud to offer 2-Aminoisobutyric Acid (CAS 62-57-7) to meet the diverse needs of the scientific community.

Understanding 2-Aminoisobutyric Acid's Significance

2-Aminoisobutyric Acid, often abbreviated as AIB, is structurally unique due to its two methyl groups attached to the alpha-carbon. This structural feature imparts distinct conformational properties when incorporated into peptide chains, influencing their stability, receptor binding affinity, and overall pharmacological profile. These characteristics make it an invaluable tool for medicinal chemists aiming to design peptide-based drugs that are resistant to enzymatic degradation and possess improved pharmacokinetic properties.

Applications in Peptide Synthesis and Drug Development

The primary application of 2-AIB lies in its use as a building block for synthetic peptides. By substituting natural amino acids with AIB, researchers can create peptides with:

  • Enhanced Stability: The steric hindrance around the alpha-carbon makes AIB-containing peptides less susceptible to proteases, leading to longer in vivo half-lives.
  • Improved Bioavailability: The unique conformational constraints can lead to better interaction with target receptors, potentially improving efficacy.
  • Novel Pharmacological Properties: AIB allows for the fine-tuning of peptide structures to achieve desired biological activities, crucial for developing targeted therapies.

Beyond peptide synthesis, 2-AIB serves as a critical intermediate in the development of various small molecule drugs and diagnostic agents. Its incorporation can modulate the physicochemical properties of drug candidates, influencing solubility, membrane permeability, and metabolic fate. For procurement professionals and R&D scientists looking to buy 2-Aminoisobutyric Acid, partnering with a reliable pharmaceutical intermediate supplier in China like us ensures access to consistent quality and competitive prices.

The Advantage of Sourcing from a Leading Manufacturer

At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to providing premium chemical compounds. Our 2-Aminoisobutyric Acid is produced through advanced fermentation techniques, ensuring high purity and a reduced environmental footprint. This sustainable approach not only aligns with modern manufacturing principles but also provides an economically viable solution for large-scale production. Whether you are conducting cutting-edge neuroscience research, developing novel bioconjugates, or synthesizing complex peptide therapeutics, our product is engineered to meet your exacting standards.

Why Choose 2-Aminoisobutyric Acid?

If your project involves the design of peptidomimetics, drug delivery systems, or compounds requiring enhanced stability and specific conformational preferences, 2-Aminoisobutyric Acid is an indispensable ingredient. Its versatility makes it a sought-after component for a wide array of applications, from fundamental biochemical research to clinical drug development.

For those seeking to purchase 2-Aminoisobutyric Acid or inquire about its price, our team is ready to assist. We understand the critical nature of your work and are dedicated to being your trusted manufacturer of this essential unnatural amino acid.