In the dynamic world of pharmaceutical research and development, the availability of high-quality, specialized chemical intermediates is paramount. Among these critical building blocks, 4-Chloro-3,5-Difluorobromobenzene (CAS: 176673-72-6) stands out for its unique structural attributes and broad synthetic utility. As a leading supplier of pharmaceutical intermediates, we understand the demands placed on R&D scientists and procurement managers seeking reliable sources for these essential materials.

Understanding the Significance of 4-Chloro-3,5-Difluorobromobenzene

This halogenated aromatic compound, characterized by its benzene ring substituted with one chlorine, two fluorine, and one bromine atom, offers a versatile platform for complex organic synthesis. The presence of these halogens, particularly fluorine, often imparts desirable properties to the final drug molecules, such as enhanced metabolic stability, improved lipophilicity, and increased binding affinity to target proteins. This makes 4-Chloro-3,5-Difluorobromobenzene a sought-after precursor in the synthesis of a wide range of Active Pharmaceutical Ingredients (APIs).

Key Applications in Pharmaceutical R&D

The utility of 4-Chloro-3,5-Difluorobromobenzene spans several critical areas within pharmaceutical synthesis:

  • Building Complex Molecular Architectures: The distinct reactivity of the carbon-halogen bonds (C-Br being generally more reactive than C-Cl and C-F in cross-coupling reactions) allows for precise, sequential functionalization. This enables chemists to construct intricate molecular scaffolds that are essential for novel drug candidates.
  • Introduction of Fluorine: Fluorine substitution is a common strategy in medicinal chemistry to modulate the pharmacokinetic and pharmacodynamic properties of drugs. As a fluorinated building block, this compound facilitates the efficient incorporation of fluorine into target molecules.
  • Intermediate for Diverse Drug Classes: While specific drug names derived directly from this compound are proprietary, it serves as a key intermediate in the development pathways for various therapeutic areas, including oncology, infectious diseases, and neurological disorders.

Why Choose Us as Your Supplier?

As a dedicated manufacturer and supplier, we pride ourselves on providing not just a chemical, but a solution. Our commitment extends beyond the product itself:

  • High Purity: We ensure that our 4-Chloro-3,5-Difluorobromobenzene meets stringent purity requirements, which is critical for reproducible and reliable synthesis outcomes in pharmaceutical manufacturing.
  • Competitive Pricing: Leveraging our manufacturing capabilities in China, we offer highly competitive prices, enabling our clients to manage R&D budgets effectively. We encourage you to request a quote for your specific needs.
  • Reliable Supply Chain: Understanding the importance of timely delivery, we maintain robust supply chains to ensure that your projects are never delayed due to material shortages. We are a trusted manufacturer and supplier ready to meet your volume demands.
  • Technical Support: Our team is equipped to provide technical insights and support, helping you maximize the utility of our products in your synthesis strategies.

For pharmaceutical manufacturers and research institutions looking to buy 4-Chloro-3,5-Difluorobromobenzene, partnering with a reliable manufacturer and supplier like us ensures access to a critical raw material that fuels innovation. We invite you to request a quote and discover how our commitment to quality and service can support your next breakthrough.