In the intricate world of pharmaceutical research and development, access to high-quality, reliable chemical intermediates is paramount. Among these vital components, 5-Bromoindoline (CAS 22190-33-6) stands out as a particularly versatile and indispensable building block. This article delves into why 5-Bromoindoline is a cornerstone for many synthesis pathways and highlights the advantages of securing this compound from a trusted manufacturer in China.

Understanding 5-Bromoindoline: Properties and Synthesis

5-Bromoindoline is a brominated indoline derivative, chemically known as 5-bromo-2,3-dihydro-1H-indole. Its molecular formula is C8H8BrN, with a molecular weight of 198.06 g/mol. Typically appearing as a white to brown low melting solid, its utility stems from the reactive bromine atom located at the 5-position of the indoline core. This specific substitution pattern opens up a wide array of chemical transformations.

The synthesis of 5-Bromoindoline often involves the deacetylation of N-acetyl-5-bromoindoline under acidic conditions, a process that yields the compound with high purity and excellent efficiency. This established synthetic route ensures that when you purchase 5-Bromoindoline, you are acquiring a product optimized for chemical applications.

Key Applications in Pharmaceutical Research

The primary driver for the demand for 5-Bromoindoline is its significant role in pharmaceutical synthesis. It serves as a crucial intermediate in the preparation of various biologically active compounds. For instance, it is instrumental in the synthesis of selective human β3 adrenergic receptor agonists, which are of interest for their therapeutic potential. Furthermore, its structure allows for targeted modifications through reactions like palladium-catalyzed cross-coupling, enabling the construction of complex molecular architectures essential for novel drug candidates.

For researchers and procurement managers in the pharmaceutical sector, the ability to buy high-purity 5-Bromoindoline is critical. It directly impacts the yield, purity, and efficacy of the final drug product. Relying on a reputable supplier ensures that these rigorous standards are met consistently.

Why Source from a China Manufacturer?

As a leading manufacturer and supplier of fine chemicals, we understand the global demand for compounds like 5-Bromoindoline. Sourcing from China offers several distinct advantages:

  • Competitive Pricing: Our optimized production facilities and economies of scale allow us to offer 5-Bromoindoline at a competitive price, making advanced chemical synthesis more accessible.
  • High Purity Standards: We adhere to stringent quality control measures to ensure our 5-Bromoindoline meets or exceeds industry purity requirements, typically 97% or higher.
  • Reliable Supply Chain: We maintain substantial stock and efficient logistics to guarantee a consistent and timely supply, crucial for uninterrupted production cycles.
  • Expertise and Support: Our team possesses deep knowledge of chemical synthesis and is ready to provide technical assistance, including COAs and MSDS, for CAS 22190-33-6.

If you are seeking a dependable source for 5-Bromoindoline, look no further. We are committed to providing the quality products and services that drive innovation in pharmaceutical R&D. Get a quote today and experience the benefits of partnering with a premier chemical supplier.