The Essential Role of Barbituric Acid in Pharmaceutical Synthesis
Barbituric acid, with its chemical formula C4H4N2O3 and CAS number 67-52-7, stands as a cornerstone organic intermediate, particularly vital within the pharmaceutical industry. As a parent compound for barbiturate drugs, its synthesis and availability are of paramount importance to researchers and manufacturers alike. This white to cream-colored crystalline powder, characterized by its odorless nature and solubility in water, possesses a unique chemical structure that makes it a versatile building block for a wide array of complex organic molecules.
The synthesis of Barbituric acid typically involves the condensation of diethyl malonate with urea. This process, while established, requires precise control to ensure the high purity (often ≥99.0%) demanded by pharmaceutical applications. Sourcing high-quality barbituric acid from reputable manufacturers, especially those based in China, can offer significant cost advantages without compromising on quality. For procurement managers and R&D scientists, understanding the nuances of sourcing, including supplier reliability and competitive pricing, is key to efficient operations. When looking to buy barbituric acid, it's crucial to consider suppliers who can provide detailed specifications, certificates of analysis, and consistent supply.
Beyond its role as a precursor to sedative and hypnotic drugs, barbituric acid itself finds application in the synthesis of Vitamin B2 and serves as a valuable intermediate for plastics and dye manufacturing. Its reactive methylene group also makes it amenable to Knoevenagel condensation, a fundamental reaction in organic synthesis for creating more complex derivatives. For those in the chemical industry, whether you are looking for barbituric acid for organic synthesis, as a pharmaceutical intermediate, or for other industrial uses, identifying a dependable manufacturer is the first step towards successful product development and commercialization. Explore pricing and supplier options from leading Chinese chemical producers to secure this essential compound for your R&D or production needs.
Perspectives & Insights
Quantum Pioneer 24
“Barbituric acid, with its chemical formula C4H4N2O3 and CAS number 67-52-7, stands as a cornerstone organic intermediate, particularly vital within the pharmaceutical industry.”
Bio Explorer X
“As a parent compound for barbiturate drugs, its synthesis and availability are of paramount importance to researchers and manufacturers alike.”
Nano Catalyst AI
“This white to cream-colored crystalline powder, characterized by its odorless nature and solubility in water, possesses a unique chemical structure that makes it a versatile building block for a wide array of complex organic molecules.”