NINGBO INNO PHARMCHEM CO.,LTD. is a leading supplier of high-quality pharmaceutical excipients, and our Copovidone (PVP/VA VA64) is a prime example of an ingredient that plays a critical role in modern tablet manufacturing. As a pharmaceutical binder, Copovidone offers exceptional performance characteristics that are vital for creating robust, consistent, and effective tablets.

The primary function of a tablet binder is to hold the ingredients of a tablet together, forming a cohesive mass that can be compressed into a solid dosage form. Copovidone excels in this role due to its strong adhesive properties. It is highly effective in both direct compression and wet granulation methods. In direct compression, where powder blends are directly compressed into tablets without prior granulation, Copovidone's binding capacity ensures the formation of hard, intact tablets. This method is favored for its efficiency and cost-effectiveness, making Copovidone a valuable excipient for such processes.

In wet granulation, Copovidone acts as a binder solution or a dry powder that is then moistened with a granulating liquid. The polymer helps to form granules with optimal size and flow properties, which are essential for uniform tablet compression. Copovidone's low hygroscopicity in wet granulation processes contributes to predictable granulation endpoints and reduces the tendency for granules to stick to processing equipment, even under challenging conditions. This reliability is crucial for consistent manufacturing outcomes.

Compared to other binders, Copovidone offers several advantages. It provides excellent plasticity, which helps to reduce tablet capping and lamination – common issues that can compromise tablet integrity. This plasticity allows the granules or powder blend to deform under pressure, forming stronger inter-particulate bonds. Furthermore, Copovidone contributes to tablet hardness and reduces friability, ensuring that tablets withstand handling and transport without breaking.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing pharmaceutical-grade Copovidone that meets the highest quality and regulatory standards, including GMP. Our consistent quality ensures that formulators can rely on Copovidone VA64 as a dependable copovidone binder for their tablet formulations, contributing to the development of safe and effective medicines. Its efficacy as a binder for pharmaceutical applications makes it an indispensable component in the production of oral solid dosage forms.