In the ever-evolving landscape of pharmaceutical science, understanding the historical trajectory of therapeutic agents offers invaluable insights for current and future research. Cisapride (CAS 81098-60-4), a compound once widely prescribed, serves as a compelling example of how scientific understanding and safety evaluations shape drug development. While its direct clinical use has been largely discontinued, its legacy persists in various research contexts.

Cisapride was primarily known as a gastroprokinetic agent, acting through the 5-HT4 receptor to enhance gastrointestinal motility. Its development marked a significant step in understanding serotonin's role in gut function. However, its association with serious cardiac arrhythmias, particularly QT prolongation and Torsades de Pointes, led to its withdrawal from many markets. This history underscores the critical importance of rigorous safety profiling in drug development, a lesson that continues to inform R&D strategies today. For those seeking to 'buy Cisapride powder' for historical reference or specific research on its pharmacological mechanisms, identifying a reliable 'Cisapride supplier for research' is essential.

Despite its clinical limitations, Cisapride remains a valuable compound for scientific inquiry. Researchers may use it to study the intricacies of the 5-HT4 receptor, investigate cardiac ion channel function (specifically the hERG channel, which it potently inhibits), or explore potential drug interactions. Accessing high-purity Cisapride from a trusted 'pharmaceutical intermediate supplier' is crucial for obtaining accurate and reproducible research outcomes. When considering 'Cisapride CAS 81098-60-4 price', it's important to balance cost with the assurance of quality and purity required for scientific studies.

The legacy of Cisapride highlights the iterative nature of pharmaceutical science. Compounds that were once mainstays can inform future developments through their study. For researchers and formulators continuing to work with this compound, partnering with a dedicated 'Cisapride manufacturer China' or an experienced global supplier ensures they have access to the necessary materials to advance scientific knowledge, contributing to the broader understanding of drug safety and efficacy.