In the rapidly advancing fields of biotechnology and pharmaceutical research, the ability to precisely modify and functionalize biomolecules is paramount. Among the array of sophisticated chemical tools available, PEGylated derivatives have emerged as indispensable components. This article delves into the significance of Biotin-PEG3-Azide (CAS 875770-34-6), a critical intermediate that combines the proven utility of biotinylation with the advantageous properties of polyethylene glycol (PEG) linkers. As a leading chemical manufacturer, we are committed to supplying high-quality Biotin-PEG3-Azide that empowers researchers and developers worldwide.

The core benefit of incorporating a PEG linker, such as the PEG3 moiety in Biotin-PEG3-Azide, lies in its ability to enhance the solubility and biocompatibility of biomolecules. This is particularly crucial when working with hydrophobic molecules or in aqueous-based biological systems. The hydrophilic nature of the PEG chain helps to shield the conjugated biomolecule, reducing aggregation and improving its overall behavior in solution. This improved solubility is a key factor in achieving consistent and reproducible results in various biochemical assays and applications.

Furthermore, the presence of the azide group on Biotin-PEG3-Azide makes it an ideal partner for click chemistry. This bioorthogonal reaction, typically between an azide and an alkyne, is highly efficient, selective, and proceeds under mild conditions, making it perfectly suited for modifying sensitive biomolecules without causing damage. By using Biotin-PEG3-Azide, researchers can readily introduce a biotin tag onto alkyne-modified targets. This biotin tag can then be utilized for a multitude of downstream applications, including immobilization onto avidin or streptavidin-coated surfaces, purification via affinity chromatography, or detection in various analytical techniques like Western blotting and ELISA.

As a dedicated supplier, we understand the critical role of purity and consistency in chemical intermediates. Our Biotin-PEG3-Azide (CAS 875770-34-6) is manufactured to high purity standards, ensuring that you receive a reliable product for your demanding research and development projects. Whether you are engaged in the synthesis of PROTACs, antibody-drug conjugates, or novel nanomaterials, our Biotin-PEG3-Azide provides a robust and versatile solution. We encourage potential B2B clients to request a quote and explore our free sample program to experience the quality and performance of our products firsthand. Partner with a trusted manufacturer for your critical chemical needs.