In the complex landscape of pharmaceutical manufacturing, the reliability and quality of intermediates are paramount. One such critical compound is 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine, identified by its CAS number 74853-08-0. This molecule serves as a cornerstone in the synthesis of Posaconazole, a broad-spectrum triazole antifungal agent recognized for its efficacy against invasive fungal infections. Understanding its importance and how to procure it efficiently is crucial for pharmaceutical companies worldwide.

Posaconazole is a vital medication, particularly for immunocompromised patients who are at high risk of developing life-threatening fungal infections. The intricate synthesis pathway of Posaconazole necessitates a high-purity intermediate like 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine. Its specific chemical structure, C16H19N3O, with a molecular weight of 269.34, provides the essential building blocks for constructing the final active pharmaceutical ingredient (API). The demand for this intermediate is directly linked to the global demand for effective antifungal treatments.

For pharmaceutical R&D departments and production managers, sourcing this intermediate reliably and cost-effectively is a key operational challenge. Leading manufacturers and suppliers, particularly those based in China, offer this product with guaranteed purity levels, often exceeding 97%. When looking to buy 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine, it is essential to partner with a supplier who can demonstrate consistent quality, competitive pricing, and a robust supply chain. This ensures uninterrupted production and adherence to stringent regulatory standards.

The process of synthesizing 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine involves complex organic chemistry, often starting from nitro-substituted precursors and employing reduction techniques. Manufacturers invest heavily in process optimization to achieve high yields and purity, making the compound suitable for GMP environments. Exploring options for bulk purchase from established suppliers can lead to significant cost savings, a critical factor in the competitive pharmaceutical market. By understanding the value of this intermediate and its role in life-saving medications, companies can make informed procurement decisions.

In conclusion, 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine is more than just a chemical compound; it is a critical enabler for antifungal therapy. Pharmaceutical companies seeking to manufacture Posaconazole or explore other novel drug candidates will find a reliable partner in experienced manufacturers and suppliers who can deliver this essential intermediate. Ensuring a stable supply of high-quality 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine is a strategic imperative for meeting global healthcare needs.