The global challenge of antibiotic resistance necessitates continuous innovation in antibacterial therapies. Central to this effort is the development and reliable supply of high-quality pharmaceutical intermediates, such as (S)-(+)-2,2-Dimethylcyclopropane Carboxamide (CAS: 75885-58-4). This compound is a cornerstone in the production of Cilastatin, a drug that significantly amplifies the power of essential antibiotics. NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer in China committed to providing this critical intermediate.

The primary function of 2,2-Dimethylcyclopropane Carboxamide is to serve as a key intermediate in the synthesis of Cilastatin. Cilastatin is a dehydropeptidase inhibitor that is administered alongside Imipenem, a broad-spectrum antibiotic. Imipenem is highly effective against many bacterial infections, but it is susceptible to rapid inactivation by enzymes found in the kidneys. Cilastatin neutralizes these enzymes, thereby preventing the premature breakdown of Imipenem. This action increases the concentration of Imipenem in the body, leading to enhanced antibacterial activity and improved therapeutic outcomes, especially in treating severe infections. The chiral purity of the 2,2-Dimethylcyclopropane Carboxamide is essential for this biological interaction to occur effectively.

As a trusted supplier of Pharmaceutical Intermediates from China, NINGBO INNO PHARMCHEM CO.,LTD. guarantees the high quality and consistency required for pharmaceutical production. Our 2,2-Dimethylcyclopropane Carboxamide exhibits excellent assay values and chiral purity, making it an ideal choice for companies engaged in complex organic synthesis. By providing reliable chiral building blocks, we empower our clients to develop safer and more potent drug formulations. The compound’s stable crystalline powder form and well-defined chemical properties further ensure its suitability for various manufacturing processes.

Choosing to source 2,2-Dimethylcyclopropane Carboxamide from NINGBO INNO PHARMCHEM CO.,LTD. offers significant advantages, including access to advanced production technologies and competitive pricing. Our strategic location in China allows us to maintain a robust supply chain and respond efficiently to market demands. For pharmaceutical companies aiming to enhance antibiotic efficacy and combat resistance, securing a reliable supply of this vital intermediate is paramount. We are dedicated to supporting the pharmaceutical industry’s mission to develop innovative treatments that safeguard public health.