The pursuit of effective cancer therapies is a continuous journey, and understanding cellular metabolism plays a pivotal role. Among the key compounds being investigated is 2-Deoxy-D-Glucose (2-DG), a non-metabolizable glucose analog with the CAS number 154-17-6. As a specialized supplier of pharmaceutical intermediates, we recognize the growing interest and critical applications of 2-DG in cutting-edge cancer research.

What Makes 2-Deoxy-D-Glucose Vital in Cancer Research?

Cancer cells often exhibit a significantly higher rate of glucose uptake and glycolysis compared to normal cells, a phenomenon known as the Warburg effect. 2-Deoxy-D-Glucose interferes with this fundamental process. When cells attempt to metabolize 2-DG, it gets phosphorylated by hexokinase but cannot proceed through the subsequent steps of glycolysis due to the absence of the 2-hydroxyl group. This effectively traps the molecule within the cell and disrupts cellular energy production, leading to reduced ATP levels. This disruption can trigger various cellular responses, including apoptosis (programmed cell death) and inhibition of cell proliferation.

Researchers utilize 2-DG to:

  • Inhibit Glycolysis: Study the impact of blocking the glycolysis pathway on cancer cell survival and growth.
  • Induce Cell Stress: Investigate how metabolic stress affects cancer cells, potentially leading to therapeutic interventions.
  • Enhance Treatment Efficacy: Explore its potential in combination therapies to sensitize cancer cells to existing treatments like chemotherapy or radiation.
  • Study Glucose Transporter Function: Understand the role of glucose transporters in cancer cell uptake.

Sourcing High-Quality 2-Deoxy-D-Glucose: Why It Matters

For researchers and pharmaceutical companies, the purity and consistency of chemical intermediates are paramount. When you look to buy 2-deoxy-D-glucose, selecting a reliable manufacturer is essential. Our commitment as a leading 2-deoxy-D-glucose supplier in China ensures that you receive a product with high purity (typically 97% Min. or higher), suitable for demanding research applications. We understand the importance of consistent quality and stable supply chains, particularly for compounds like 2-DG that are integral to critical studies.

The Benefits of Partnering with Our Company

As a dedicated manufacturer, we offer:

  • Guaranteed Purity: Our 2-Deoxy-D-Glucose is tested to meet stringent quality controls.
  • Competitive Pricing: We provide affordable solutions for your research needs, making high-quality chemicals accessible.
  • Reliable Supply Chain: Benefit from consistent availability and timely delivery from our production facilities.
  • Expert Support: Our team can provide technical information and assist with your procurement needs.

By choosing us as your 2-deoxy-D-glucose manufacturer, you are investing in the quality and reliability that your research demands. We are proud to support advancements in cancer treatment and metabolic research by providing essential building blocks like 2-DG. If you are looking to purchase 2-deoxy-D-glucose or inquire about its price, please do not hesitate to contact us.