In the dynamic landscape of pharmaceutical research and development, the identification and synthesis of novel chemical entities are paramount. Among the myriad of building blocks available to medicinal chemists, 2-Fluoro-3-iodopyridine stands out as a particularly versatile and impactful intermediate. Its unique structural features, specifically the presence of both fluorine and iodine atoms on a pyridine ring, imbue it with exceptional reactivity and utility in the construction of complex molecular architectures.

The significance of 2-Fluoro-3-iodopyridine (CAS 113975-22-7) in modern drug discovery cannot be overstated. This compound serves as a crucial precursor in the synthesis of a wide range of biologically active molecules. Its strategic placement of halogen substituents allows for a variety of cross-coupling reactions, such as Suzuki, Stille, and Sonogashira couplings, which are cornerstones of contemporary synthetic organic chemistry. These reactions enable the efficient introduction of diverse functional groups and substituents onto the pyridine core, a common motif in many pharmaceutical agents.

One of the most prominent areas where 2-Fluoro-3-iodopyridine demonstrates its value is in the development of targeted therapies for diseases like cancer and inflammatory conditions. Researchers frequently utilize this intermediate to synthesize drug candidates that exhibit enhanced efficacy and improved pharmacokinetic profiles. The fluorine atom can influence lipophilicity and metabolic stability, while the iodine atom serves as an excellent leaving group for carbon-carbon bond formation. By leveraging these properties, scientists can design molecules with greater specificity and reduced off-target effects.

For procurement managers and R&D scientists seeking reliable sources, understanding the availability and pricing of high-purity 2-Fluoro-3-iodopyridine is essential. Several reputable manufacturers and suppliers, particularly in China, offer this compound with purity levels typically exceeding 98%. When looking to buy 2-Fluoro-3-iodopyridine, it is advisable to partner with suppliers who can guarantee consistent quality, efficient delivery, and competitive pricing. This ensures that your research and production pipelines remain uninterrupted and cost-effective.

The synthesis of 2-Fluoro-3-iodopyridine itself often involves lithiation of 2-fluoropyridine followed by iodination, a process that requires precise control of reaction conditions to achieve high yields and purity. As a leading chemical supplier, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing researchers and manufacturers with premium intermediates like 2-Fluoro-3-iodopyridine, supporting their endeavors in creating next-generation pharmaceuticals and agrochemicals. We encourage you to inquire about our bulk purchase options and to request a quote for your specific project needs, ensuring you have a dependable supplier for this vital chemical building block.