In the intricate world of pharmaceutical development, the selection of high-quality intermediates is paramount to the success of drug synthesis. Among these crucial building blocks, 2,3,4,5-Tetrafluorobenzoic Acid (CAS 1201-31-6) stands out for its unique properties and significant applications, particularly in the creation of advanced antimicrobial agents. As a leading supplier of fine chemicals, understanding the role and sourcing of this compound is vital for pharmaceutical manufacturers and research scientists.

What is 2,3,4,5-Tetrafluorobenzoic Acid?

2,3,4,5-Tetrafluorobenzoic Acid is a highly fluorinated aromatic carboxylic acid. Its structure, featuring four fluorine atoms strategically placed on the benzene ring, imbues it with distinctive chemical characteristics. These include enhanced reactivity, thermal stability, and specific electronic properties that are highly sought after in advanced organic synthesis. The compound's molecular formula is C7H2F4O2, with a molecular weight of 194.08 g/mol.

Key Application: Intermediate for Lomefloxacin Synthesis

One of the most significant applications of 2,3,4,5-Tetrafluorobenzoic Acid is its role as a key intermediate in the synthesis of lomefloxacin. Lomefloxacin is a third-generation fluoroquinolone antibiotic, known for its broad-spectrum activity against various bacterial infections. The incorporation of the tetrafluorinated phenyl group, derived from this acid, is critical for the pharmacological profile and efficacy of lomefloxacin. For pharmaceutical companies looking to buy high-purity intermediates for antibiotic production, sourcing reliable 2,3,4,5-Tetrafluorobenzoic Acid is a top priority.

Beyond Pharmaceuticals: Other Industrial Uses

While its role in pharmaceutical synthesis is prominent, 2,3,4,5-Tetrafluorobenzoic Acid also finds utility in other specialized industrial applications. It serves as a valuable precursor in the development of agrochemicals, contributing to the creation of effective pesticides and crop protection agents. Furthermore, its unique properties make it suitable for use in the preparation of advanced liquid crystal materials, impacting the performance of modern display technologies. Researchers in materials science also utilize it for developing specialty polymers requiring enhanced chemical resistance and thermal stability.

Sourcing and Quality Considerations for Buyers

When sourcing 2,3,4,5-Tetrafluorobenzoic Acid, buyers often look for a reliable manufacturer that guarantees high purity (typically ≥98% by HPLC) and consistent quality. Factors such as accurate specifications, adherence to quality standards (like ISO 9001), and secure packaging are essential. For procurement managers, identifying a trusted supplier in China that can offer competitive pricing, bulk quantities, and efficient delivery is key to managing production costs and ensuring supply chain stability.

As a dedicated supplier of fine chemical intermediates, we understand the critical demands of the pharmaceutical and chemical industries. We offer high-purity 2,3,4,5-Tetrafluorobenzoic Acid, ensuring that our clients receive a product that meets stringent quality requirements for their complex synthesis needs. If you are looking to buy this essential intermediate, consider partnering with a manufacturer committed to excellence and customer satisfaction.