The Role of 4-Bromo-2-fluoropyridine in Advanced Pharmaceutical Synthesis
In the dynamic world of pharmaceutical development, the precise selection of building blocks is paramount. Among these, heterocyclic compounds play a significant role, and 4-Bromo-2-fluoropyridine (CAS 128071-98-7) stands out as a crucial intermediate. Its unique combination of fluorine and bromine atoms on a pyridine ring makes it an invaluable tool for chemists engaged in the synthesis of complex organic molecules, particularly those targeting specific therapeutic pathways.
The primary utility of 4-Bromo-2-fluoropyridine lies in its application for the synthesis of isoquinolinone derivatives. These derivatives are of considerable interest in medicinal chemistry due to their potential therapeutic applications, most notably in the development of inhibitors for poly(ADP-ribose)polymerase-1 (PARP-1). PARP-1 is a key enzyme involved in DNA repair, and its inhibition has emerged as a promising strategy for treating various cancers. By providing a reactive site for nucleophilic substitution and cross-coupling reactions, this intermediate enables the efficient construction of these complex isoquinolinone scaffolds. If you are looking to buy high-quality 4-Bromo-2-fluoropyridine for your PARP-1 inhibitor research, understanding its role is crucial.
As a leading manufacturer and supplier of specialty chemicals, we understand the importance of consistent quality and reliable supply. Our 4-Bromo-2-fluoropyridine is produced with a minimum purity of 99%, ensuring that researchers and formulators can depend on it for reproducible results in their synthesis. Sourcing from a reputable Chinese manufacturer like us offers distinct advantages, including competitive price points and the assurance of a robust supply chain, critical for both laboratory-scale research and larger production runs. When seeking a dependable source, consider requesting a quote for bulk quantities.
The versatility of 4-Bromo-2-fluoropyridine extends beyond PARP-1 inhibitors. Its pyridine core and halogen substituents make it a valuable building block for a wide array of organic synthesis projects, including the development of agrochemicals, materials science compounds, and other fine chemicals. Researchers often search for specific long-tail keywords such as 'pharmaceutical intermediate CAS 128071-98-7' or '2-fluoro-4-bromopyridine chemical synthesis' to find reliable sources. For those involved in drug discovery, securing a consistent supply of such intermediates is as important as the research itself. We encourage you to explore our product offerings and learn how our commitment to quality and service can support your R&D objectives.
Perspectives & Insights
Chem Catalyst Pro
“In the dynamic world of pharmaceutical development, the precise selection of building blocks is paramount.”
Agile Thinker 7
“Among these, heterocyclic compounds play a significant role, and 4-Bromo-2-fluoropyridine (CAS 128071-98-7) stands out as a crucial intermediate.”
Logic Spark 24
“Its unique combination of fluorine and bromine atoms on a pyridine ring makes it an invaluable tool for chemists engaged in the synthesis of complex organic molecules, particularly those targeting specific therapeutic pathways.”