The Role of 4-Chloro-2-fluorobenzoic Acid in Modern Chemical Synthesis
In the intricate world of chemical manufacturing, specific intermediates play pivotal roles in enabling the synthesis of complex and high-value compounds. Among these, 4-Chloro-2-fluorobenzoic acid (CAS 446-30-0) stands out as a versatile and essential building block, particularly within the pharmaceutical and agrochemical sectors. As a leading fine chemical supplier, understanding the applications and sourcing of such compounds is crucial for procurement managers and R&D scientists.
4-Chloro-2-fluorobenzoic acid is characterized by its white to light yellow crystalline powder appearance and possesses a molecular formula of C7H4ClFO2, with a molecular weight of 174.56. This structure, featuring both chlorine and fluorine atoms on a benzoic acid core, imparts unique reactivity and properties, making it highly sought after in various synthetic pathways. Its utility spans from the development of targeted fungicides and herbicides in the agricultural industry to its application as a key intermediate in the creation of novel pharmaceuticals, including ATX inhibitors, NHE3 inhibitors, and NMDA receptor antagonists.
For businesses looking to buy 4-Chloro-2-fluorobenzoic acid, sourcing from a reputable manufacturer in China is often a strategic choice. This ensures not only competitive pricing but also access to substantial supply capacities, vital for both R&D projects and large-scale production runs. When selecting a supplier, it's important to verify the purity specifications, typically needing ≥99.0% (HPLC) for demanding applications. This level of quality assurance is paramount for predictable reaction outcomes and the ultimate efficacy of the final product.
The versatility of 4-Chloro-2-fluorobenzoic acid as a pharmaceutical intermediate cannot be overstated. Its specific halogen substitution pattern allows chemists to introduce precise modifications into drug molecules, influencing their pharmacokinetic and pharmacodynamic profiles. Procurement managers often search for terms like 'CAS 446-30-0 supplier' or 'wholesale 4-Chloro-2-fluorobenzoic acid for synthesis' to identify reliable sources. Engaging with established suppliers provides access to crucial documentation, such as Certificates of Analysis (CoA) and Safety Data Sheets (SDS), which are indispensable for regulatory compliance and safe handling.
Beyond pharmaceuticals, its role in agrochemical synthesis is equally significant. The ability to modify biological activity through fluorination and chlorination makes it a valuable component in developing next-generation crop protection agents. Researchers investigating '2-Fluoro-4-chlorobenzoic acid applications' will find its utility in formulating products that offer improved efficacy and potentially reduced environmental impact.
For companies planning to purchase 4-Chloro-2-fluorobenzoic acid, partnering with a manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ensures a reliable and high-quality supply. We are committed to supporting your chemical needs, providing not just the material but also the technical expertise to facilitate your projects. From initial inquiry to final delivery, our focus is on providing efficient service and superior products, making us your go-to source for essential fine chemical intermediates.
Perspectives & Insights
Logic Thinker AI
“Beyond pharmaceuticals, its role in agrochemical synthesis is equally significant.”
Molecule Spark 2025
“The ability to modify biological activity through fluorination and chlorination makes it a valuable component in developing next-generation crop protection agents.”
Alpha Pioneer 01
“Researchers investigating '2-Fluoro-4-chlorobenzoic acid applications' will find its utility in formulating products that offer improved efficacy and potentially reduced environmental impact.”