In the demanding field of pharmaceutical research and development, the quality and availability of chemical intermediates are paramount. 4-Chloromethyl-5-methyl-1,3-dioxol-2-one (CAS 80841-78-7) stands as a critical molecule, instrumental in the synthesis of advanced therapeutic agents. This article provides an in-depth look at its chemical properties, applications, and the importance of sourcing it from reliable manufacturers to meet stringent industry standards.

With a chemical formula of C5H5ClO3 and a molecular weight of 148.54 g/mol, 4-Chloromethyl-5-methyl-1,3-dioxol-2-one is characterized by its light yellow to yellow liquid appearance. Its primary utility is as a key intermediate in the synthesis of Olmesartan Medoxomil, a widely used drug for treating hypertension. The precise stereochemistry and purity of this intermediate are crucial for the efficacy of the final API. For researchers and procurement specialists, understanding these technical aspects ensures that the materials they buy align with the rigorous requirements of pharmaceutical synthesis.

The compound's role extends to the preparation of ampicillin prodrugs. By modifying the ampicillin molecule, prodrugs can offer improved pharmacokinetic profiles, such as enhanced oral bioavailability or targeted delivery. The functional groups present in 4-Chloromethyl-5-methyl-1,3-dioxol-2-one make it an ideal building block for these sophisticated modifications. Therefore, securing a consistent supply from a reputable manufacturer is vital for companies developing next-generation antibiotics.

When considering where to purchase this essential intermediate, factors such as purity (often specified as ≥99.0%), assay consistency, and production capacity are key differentiators. Our facility in China is equipped with advanced manufacturing capabilities, allowing us to offer a stable output of 15 metric tons per month. We provide comprehensive technical support, including Certificates of Analysis (COA), to assure our clients of the product's quality and specifications. This commitment ensures that our clients receive materials that can be directly integrated into their demanding production processes.

The market for pharmaceutical intermediates is global, and it is essential to partner with suppliers who not only offer competitive pricing but also demonstrate a deep understanding of regulatory requirements and quality control. We aim to be that partner, providing high-quality 4-Chloromethyl-5-methyl-1,3-dioxol-2-one with exceptional service. By choosing us as your supplier, you gain access to a reliable source of this critical chemical, supporting your ongoing research and production needs.