The Role of 4-Hydroxy-3-nitrobenzoic Acid in Modern Pharmaceutical Synthesis
In the intricate world of pharmaceutical development, the quality and reliability of chemical intermediates are paramount. One such crucial compound is 4-Hydroxy-3-nitrobenzoic Acid, identified by CAS number 616-82-0. This aromatic carboxylic acid, featuring both hydroxyl and nitro functional groups, acts as a fundamental building block in the synthesis of a wide array of complex organic molecules, many of which find application as active pharmaceutical ingredients (APIs) or their precursors. Understanding its properties and procurement channels is vital for any R&D scientist or procurement manager in the pharma sector.
The chemical structure of 4-Hydroxy-3-nitrobenzoic Acid lends itself to diverse chemical reactions, including esterification, amidation, and further functional group modifications. Its nitro group can be readily reduced to an amine, opening pathways to a vast range of nitrogen-containing heterocycles and other amine derivatives, which are common motifs in many drug molecules. The hydroxyl group also offers a site for etherification or esterification, further expanding its synthetic utility. As a manufacturer specializing in fine chemicals and pharmaceutical intermediates, we ensure that our 4-Hydroxy-3-nitrobenzoic Acid is produced to high purity standards, typically 97% minimum assay, which is critical for reproducible and efficient downstream syntheses.
For procurement professionals seeking to buy 4-Hydroxy-3-nitrobenzoic Acid, identifying a reputable supplier is key. Manufacturers and suppliers in China have become significant global players, offering competitive pricing and robust production capabilities. When sourcing this chemical, it's advisable to look for suppliers who can provide comprehensive technical data sheets, consistent product quality, and reliable delivery schedules. Enquiries for pricing and bulk orders are common, as many pharmaceutical companies require significant quantities for their clinical trials and commercial production. The ability to secure a stable supply chain for intermediates like 4-Hydroxy-3-nitrobenzoic Acid directly impacts the pace and success of drug development projects.
The role of 4-Hydroxy-3-nitrobenzoic Acid in the synthesis of anti-inflammatory and antibacterial agents, as well as other therapeutic classes, highlights its importance. Its incorporation into molecular scaffolds allows for the fine-tuning of pharmacological properties, such as efficacy, bioavailability, and metabolic stability. As the pharmaceutical industry continues to innovate, the demand for high-quality, reliably sourced intermediates like 4-Hydroxy-3-nitrobenzoic Acid will only grow. We pride ourselves on being a trusted manufacturer and supplier, dedicated to meeting the stringent requirements of the pharmaceutical industry, providing not just a product, but a partnership for successful chemical sourcing.
Perspectives & Insights
Molecule Vision 7
“When sourcing this chemical, it's advisable to look for suppliers who can provide comprehensive technical data sheets, consistent product quality, and reliable delivery schedules.”
Alpha Origin 24
“Enquiries for pricing and bulk orders are common, as many pharmaceutical companies require significant quantities for their clinical trials and commercial production.”
Future Analyst X
“The ability to secure a stable supply chain for intermediates like 4-Hydroxy-3-nitrobenzoic Acid directly impacts the pace and success of drug development projects.”