In the intricate world of pharmaceutical manufacturing, the quality and availability of intermediates are paramount. Among these essential building blocks, 4-Hydroxythiobenzamide (CAS 25984-63-8) stands out for its critical role in the synthesis of advanced therapeutic agents. As a reputable chemical supplier and manufacturer, we understand the demand for high-purity compounds that meet stringent pharmaceutical standards. This article delves into the significance of 4-Hydroxythiobenzamide, its applications, and why sourcing it from a reliable manufacturer is crucial for your research and production needs.

Understanding 4-Hydroxythiobenzamide (CAS 25984-63-8)

4-Hydroxythiobenzamide is a chemical compound with the molecular formula C7H7NOS. It typically appears as a white to light yellow powder. Its primary significance in the pharmaceutical industry lies in its function as a key intermediate in the synthesis of Febuxostat. Febuxostat is a potent non-purine selective inhibitor of xanthine oxidase, widely used for the treatment of hyperuricemia and gout, a condition characterized by elevated uric acid levels in the blood.

The synthesis pathway for Febuxostat heavily relies on intermediates like 4-Hydroxythiobenzamide, requiring high purity levels to ensure the efficacy and safety of the final drug product. Manufacturers producing this intermediate must adhere to rigorous quality control measures to guarantee a minimum assay of 99.0% or higher, as well as compliance with international standards such as USP, BP, and EP. This commitment to quality ensures that downstream processes are not compromised and that the final API meets all regulatory requirements.

Key Applications in Drug Development

Beyond its well-established role in Febuxostat synthesis, 4-Hydroxythiobenzamide also finds application in other areas of pharmaceutical research and development:

  • Organic Synthesis Intermediate: Its chemical structure makes it a valuable intermediate for various organic synthesis reactions, enabling the creation of complex molecules for novel drug candidates.
  • CDK5 Inhibitor Synthesis: Research indicates its use in the synthesis of potent CDK5 inhibitors, which are being investigated for their potential in treating neurodegenerative diseases like Alzheimer's disease.
  • PPARα Agonist Synthesis: The compound is also utilized in the creation of PPARα agonists, which are crucial in research for increasing HDL cholesterol levels and managing cardiovascular health.

These diverse applications highlight the compound's versatility and its importance across different therapeutic research avenues. For any research scientist or procurement manager looking to buy 4-Hydroxythiobenzamide, understanding these applications is key to ensuring the right material is sourced for the intended purpose.

Why Choose a Reliable Manufacturer and Supplier?

When sourcing pharmaceutical intermediates, the reliability of the manufacturer and supplier is non-negotiable. As a dedicated manufacturer of 4-Hydroxythiobenzamide in China, we offer several advantages:

  • Guaranteed Purity and Quality: We maintain strict quality control protocols to ensure our 4-Hydroxythiobenzamide consistently meets or exceeds the required purity standards. Our products are often accompanied by GMP and SGS certifications, providing an extra layer of assurance.
  • Competitive Pricing: By optimizing our manufacturing processes and supply chain, we are able to offer competitive prices for 4-Hydroxythiobenzamide, making it accessible for both R&D projects and large-scale commercial production.
  • Stable Supply Chain: We pride ourselves on our ability to provide a stable and consistent supply of this critical intermediate, minimizing disruptions to your manufacturing schedules.
  • Direct Sourcing Support: We facilitate direct purchase and provide necessary technical documentation, such as SDS and TDS, to support your procurement and research needs.

For businesses seeking to procure 4-Hydroxythiobenzamide, partnering with a knowledgeable and dependable supplier like ourselves is essential. We are committed to supporting your pharmaceutical endeavors by providing high-quality chemical raw materials and intermediates that drive innovation and product success. Explore our offerings and contact us to discuss your specific requirements for 4-Hydroxythiobenzamide.