The pharmaceutical industry relies heavily on a diverse range of chemical intermediates to construct complex Active Pharmaceutical Ingredients (APIs). Among these critical building blocks is 4-Methyl-1-piperazinecarbonyl Chloride Hydrochloride (CAS 55112-42-0). Understanding its properties and applications is essential for API manufacturers, R&D scientists, and procurement specialists seeking to buy this vital compound.

4-Methyl-1-piperazinecarbonyl Chloride Hydrochloride is characterized by its chemical structure, featuring a piperazine ring substituted with a methyl group and a carbonyl chloride moiety, complexed as a hydrochloride salt. This specific arrangement makes it a versatile intermediate, particularly for introducing the 4-methylpiperazine-1-carbonyl group into larger molecular frameworks. The high purity, often exceeding 99.0%, offered by leading manufacturers and suppliers, is crucial for ensuring the efficacy and safety of the final API.

Its primary application lies in the synthesis of various pharmaceutical compounds. The carbonyl chloride group is highly reactive, readily undergoing nucleophilic substitution reactions with amines, alcohols, and other nucleophiles. This reactivity allows it to serve as a key component in the assembly of APIs used in a wide spectrum of therapeutic areas. For example, it can be instrumental in forming amide linkages, a common feature in many drug molecules.

For manufacturers looking to purchase 4-Methyl-1-piperazinecarbonyl Chloride Hydrochloride, selecting a reliable supplier is paramount. Companies that specialize in pharmaceutical intermediates and fine chemicals, especially those based in China, are often well-positioned to provide this material. These manufacturers typically adhere to stringent quality control protocols, ensuring batch-to-batch consistency, which is non-negotiable in pharmaceutical production. When sourcing, it's beneficial to inquire about the supplier's production capacity, quality certifications, and their ability to provide necessary documentation such as Certificates of Analysis (CoA).

The price of 4-Methyl-1-piperazinecarbonyl Chloride Hydrochloride can vary depending on the supplier, order volume, and specific purity requirements. However, as an intermediate, its cost-effectiveness is a significant factor in the overall economic viability of an API. Working with manufacturers directly can often lead to more competitive pricing, especially for large-scale orders. Planning your procurement well in advance and obtaining multiple quotes from trusted suppliers can help optimize your budget.

In essence, 4-Methyl-1-piperazinecarbonyl Chloride Hydrochloride (CAS 55112-42-0) is more than just a chemical; it is a cornerstone in the creation of life-saving medicines. Its specific chemical reactivity, combined with the assurance of high purity from trusted manufacturers and suppliers, makes it an indispensable intermediate. For any organization involved in API synthesis, understanding and securing a consistent supply of this compound is a critical strategic step.