In the intricate world of pharmaceutical synthesis, certain chemical compounds stand out due to their indispensable role as intermediates in the creation of vital medications. One such compound is 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride, identified by CAS number 312753-53-0. This molecule serves as a crucial building block, primarily in the synthesis of Indacaterol, a significant API used in respiratory therapies. This article explores the importance of this intermediate, highlighting its chemical properties and applications for R&D scientists and procurement managers seeking reliable chemical raw materials.

5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride is characterized by its white to off-white powder appearance and typically exhibits a high purity, often exceeding 98.0%. This level of purity is essential for its function as a pharmaceutical intermediate. The chemical structure of this compound, featuring a diethyl-substituted indane ring system with an amine group, makes it perfectly suited for further chemical transformations required to construct more complex drug molecules.

The primary application that drives the demand for this intermediate is its use in the synthesis pathway of Indacaterol. Indacaterol is a long-acting beta-adrenoceptor agonist (LABA) widely prescribed for the management of chronic obstructive pulmonary disease (COPD). The development of such advanced therapeutics relies heavily on the availability of high-quality intermediates that can be reliably converted into the final API. Therefore, when researchers are developing or optimizing Indacaterol synthesis, the consistent supply of 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride from a trusted manufacturer becomes a critical factor for project success.

For procurement managers, sourcing this specific intermediate requires careful evaluation of suppliers. Factors such as consistent quality, competitive pricing, and secure supply chain management are paramount. Understanding the compound's CAS number (312753-53-0) is essential for accurate sourcing and comparison of offers from various manufacturers. When you decide to buy this compound, looking for suppliers that offer it in standard packaging, such as 25 kg drums, and can accommodate custom packaging needs, ensures flexibility for different operational scales.

Beyond its role in Indacaterol synthesis, 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride also finds utility in broader organic synthesis research. Its specific structural features can be leveraged by chemists to explore novel synthetic routes or create other complex organic molecules with potential pharmacological activities. As a versatile intermediate, its availability to the scientific community supports ongoing innovation in medicinal chemistry.

In summary, 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride is more than just a chemical compound; it's a vital link in the chain of pharmaceutical innovation. Its crucial role in Indacaterol synthesis underscores the importance of sourcing high-purity intermediates from reliable manufacturers. For those involved in pharmaceutical R&D and manufacturing, understanding the properties and applications of this compound, and securing a dependable supply, is key to advancing therapeutic solutions.