In the dynamic landscape of pharmaceutical research and development, the availability of high-quality chemical intermediates is paramount. Among these, 5-Aminoindan-1-one (CAS: 3470-54-0) stands out as a critical building block, instrumental in the synthesis of a wide array of Active Pharmaceutical Ingredients (APIs). Understanding its properties, synthesis routes, and the importance of sourcing from reputable manufacturers is key for R&D scientists and procurement managers alike.

What is 5-Aminoindan-1-one?

5-Aminoindan-1-one, also known by its IUPAC name 5-amino-2,3-dihydro-1H-inden-1-one, is an organic compound characterized by its indanone structure. This fused ring system, combined with an amino group at the 5-position, imparts unique reactivity and makes it a versatile intermediate in organic synthesis. Typically appearing as a solid, its solubility in polar organic solvents aids in various reaction processes.

Key Properties and Synthesis

With a molecular formula of C9H9NO and a molecular weight of approximately 147.17 g/mol, 5-Aminoindan-1-one possesses a melting point typically around 184-186°C. Its synthesis often involves reactions starting from 1-indanone. The precise control over reaction conditions and purification is vital to achieve the high purity required for pharmaceutical applications. For researchers looking to buy 5-aminoindan-1-one, ensuring a purity of 97% or higher is a common requirement, as it directly impacts the efficacy and safety of the final drug product.

Applications in Drug Discovery

The significance of 5-Aminoindan-1-one lies in its extensive use as a precursor in the synthesis of various pharmaceuticals. It has been identified as a key intermediate in the development of compounds exhibiting therapeutic effects, such as those used for treating central nervous system disorders like anxiety and depression. Its structure allows for diverse functionalizations, enabling medicinal chemists to design and synthesize novel drug candidates with targeted pharmacological activities. The demand for this compound continues to grow as pharmaceutical companies push the boundaries of drug discovery.

Sourcing from a Reliable Manufacturer in China

For procurement managers and R&D teams, securing a stable and high-quality supply of chemical intermediates is a strategic imperative. China has emerged as a global hub for chemical manufacturing, offering competitive pricing and a vast production capacity. When seeking to purchase 5-aminoindan-1-one, it is crucial to partner with a reputable manufacturer and supplier that prioritizes quality control, consistency, and regulatory compliance. A trusted supplier will provide detailed product specifications, Certificates of Analysis (CoA), and ensure timely delivery, facilitating seamless integration into your research or production workflows. Engaging with a reliable China supplier for your 5-aminoindan-1-one needs can significantly streamline your procurement process and enhance your project's success.