In the dynamic field of pharmaceutical research and development, the availability of high-quality chemical intermediates is paramount. Among these, fluorinated aromatic compounds play a significant role due to their unique electronic properties and ability to influence drug efficacy and metabolism. One such crucial compound is 5-Bromo-2,3-difluoroanisole, identified by its CAS number 261762-35-0.

This article delves into the significance of 5-Bromo-2,3-difluoroanisole as a key building block in modern pharmaceutical synthesis. We will explore its chemical characteristics, applications, and the advantages of procuring it from reputable manufacturers, especially those based in China, known for their extensive chemical production capabilities.

Understanding 5-Bromo-2,3-difluoroanisole

5-Bromo-2,3-difluoroanisole is an organic compound characterized by a benzene ring substituted with a bromine atom, two fluorine atoms, and a methoxy group. Its chemical formula is C7H5BrF2O, and it has a molecular weight of 223.01. Typically appearing as a white crystalline powder, it possesses a melting point range of 33-35°C, a boiling point of approximately 193.7°C, and a density of around 1.615 g/cm³. These properties make it amenable to various chemical reactions and purification processes.

Applications in Pharmaceutical Synthesis

The strategic placement of fluorine atoms and the bromine substituent on the anisole core makes 5-Bromo-2,3-difluoroanisole an exceptionally valuable intermediate in the synthesis of complex organic molecules. Its primary utility lies in its ability to undergo various coupling reactions, nucleophilic substitutions, and functional group transformations. This versatility allows R&D scientists and product formulators to introduce specific structural motifs necessary for the development of novel active pharmaceutical ingredients (APIs).

Researchers often leverage this compound to synthesize drug candidates targeting a wide range of therapeutic areas. The presence of fluorine can enhance lipophilicity, metabolic stability, and binding affinity of the final drug molecule. The bromine atom, acting as a good leaving group, is also instrumental in cross-coupling reactions, a cornerstone of modern synthetic organic chemistry.

Why Source from a China Manufacturer?

For procurement managers and R&D teams, sourcing critical chemical intermediates requires a balance of quality, cost, and reliability. China has emerged as a global leader in the chemical manufacturing sector, offering a vast array of intermediates like 5-Bromo-2,3-difluoroanisole at competitive prices. When you look to buy 5-Bromo-2,3-difluoroanisole online, partnering with a reputable 5-Bromo-2,3-difluoroanisole manufacturer in China offers significant advantages.

These advantages include access to large-scale production capacities, stringent quality control measures, and a deep understanding of global regulatory requirements. Furthermore, the competitive 5-Bromo-2,3-difluoroanisole price from these manufacturers can substantially impact the overall R&D budget, making it more feasible to acquire the necessary quantities for extensive research and pilot-scale production.

Ensuring Quality and Availability

When selecting a CAS 261762-35-0 chemical intermediate, it is crucial to ensure that the supplier can provide comprehensive technical documentation, such as Certificates of Analysis (CoA) and Safety Data Sheets (SDS). These documents verify the product's specifications, purity, and safe handling procedures. Building a relationship with a reliable pharmaceutical synthesis building block supplier means securing a consistent supply chain, which is vital for project timelines and the uninterrupted progression of drug development.

In conclusion, 5-Bromo-2,3-difluoroanisole is a pivotal chemical intermediate for the pharmaceutical industry. Its unique chemical structure and reactivity profile make it indispensable for synthesizing innovative drug compounds. By choosing to partner with experienced manufacturers and suppliers, particularly those in China, you can ensure the quality, affordability, and availability necessary to drive your pharmaceutical research forward.