The Role of Apremilast Intermediates in Modern Drug Synthesis
In the intricate world of pharmaceutical manufacturing, the quality and availability of key intermediates are paramount. One such vital compound is 1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanamine, identified by CAS number 253168-94-4. This chemical entity serves as a crucial building block in the synthesis of Apremilast, a widely used medication for treating inflammatory conditions such as psoriatic arthritis and plaque psoriasis. As a manufacturer specializing in high-purity pharmaceutical intermediates, understanding the significance of this compound is key to supporting drug development and production.
The synthesis of Apremilast is a multi-step process, and the reliability of each intermediate directly impacts the yield and purity of the final Active Pharmaceutical Ingredient (API). 1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanamine plays a pivotal role in establishing the core structure of Apremilast. Its specific chemical properties, including its appearance as a white to off-white powder, are carefully controlled to ensure optimal reactivity and minimal side reactions during synthesis. For R&D scientists and procurement managers, sourcing this intermediate from a reputable supplier in China or globally is a strategic decision that influences project timelines and product efficacy.
When looking to buy or purchase 1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanamine, discerning buyers prioritize not only competitive price but also consistent quality and reliable supply. The market offers various grades and purities, but for pharmaceutical applications, a purity of 98% or higher is often a non-negotiable requirement. This ensures that impurities are minimized, which is critical for meeting regulatory standards and patient safety. Therefore, partnering with a manufacturer that demonstrates robust quality control measures and transparent documentation is essential.
The journey from raw material to finished pharmaceutical product is complex. Intermediates like CAS 253168-94-4 are the unsung heroes, enabling the creation of life-changing medications. By understanding the chemical synthesis pathways and the importance of each component, pharmaceutical companies can streamline their production processes. If you are seeking a dependable supplier for your Apremilast intermediate needs, focusing on companies that offer detailed technical specifications, Certificates of Analysis (CoA), and a proven track record in pharmaceutical chemical supply is highly recommended. This proactive approach ensures the success of your drug development and manufacturing endeavors.
Perspectives & Insights
Logic Thinker AI
“This chemical entity serves as a crucial building block in the synthesis of Apremilast, a widely used medication for treating inflammatory conditions such as psoriatic arthritis and plaque psoriasis.”
Molecule Spark 2025
“As a manufacturer specializing in high-purity pharmaceutical intermediates, understanding the significance of this compound is key to supporting drug development and production.”
Alpha Pioneer 01
“The synthesis of Apremilast is a multi-step process, and the reliability of each intermediate directly impacts the yield and purity of the final Active Pharmaceutical Ingredient (API).”