The Role of Benzofuran-6-Carboxylic Acid in Ophthalmic Drug Development
The development of advanced pharmaceutical treatments often hinges on the availability of highly specialized chemical intermediates. Benzofuran-6-carboxylic Acid (CAS: 77095-51-3) plays a particularly crucial role in the ophthalmic sector, notably as an intermediate in the synthesis of Lifitegrast, a widely used medication for dry eye disease. NINGBO INNO PHARMCHEM CO.,LTD., a leading manufacturer of fine chemical intermediates, recognizes the critical importance of this compound and is dedicated to providing a reliable and high-quality supply to the pharmaceutical industry.
Lifitegrast's effectiveness in treating dry eye symptoms is well-documented, and its production relies on a series of precise chemical reactions. Benzofuran-6-carboxylic Acid is a key molecular component that contributes significantly to the final structure and therapeutic properties of Lifitegrast. For companies engaged in the research, development, or manufacturing of ophthalmic solutions, securing a consistent supply of this intermediate is a strategic imperative. Buyers often search for specific product details, including 'benzofuran-6-carboxylic acid synthesis' and 'benzofuran-6-carboxylic acid supplier', to identify reliable sources for their needs.
The pharmaceutical industry demands intermediates of exceptional purity and consistent quality. NINGBO INNO PHARMCHEM CO.,LTD. has invested in optimizing the manufacturing process for Benzofuran-6-carboxylic Acid. Our improved synthetic route, originating from 4-bromo-2-hydroxybenzaldehyde, not only achieves a superior yield (78%) but also bypasses harsh reaction conditions, contributing to a safer and more sustainable production process. This focus on efficiency and quality is essential for any manufacturer looking to buy this intermediate for large-scale production.
Furthermore, the advancements in the synthesis of Lifitegrast itself, including the optimization of the hydrolysis step that leads to a final product with >99.9% purity and an overall yield of 79%, underscore the importance of high-grade starting materials. As a trusted manufacturer in China, we ensure that our Benzofuran-6-carboxylic Acid meets the rigorous standards required for ophthalmic drug development. We encourage pharmaceutical professionals to contact us for detailed specifications, competitive pricing, and to secure a dependable supply of this vital intermediate for their innovative therapies.
Perspectives & Insights
Logic Thinker AI
“Buyers often search for specific product details, including 'benzofuran-6-carboxylic acid synthesis' and 'benzofuran-6-carboxylic acid supplier', to identify reliable sources for their needs.”
Molecule Spark 2025
“The pharmaceutical industry demands intermediates of exceptional purity and consistent quality.”
Alpha Pioneer 01
“has invested in optimizing the manufacturing process for Benzofuran-6-carboxylic Acid.”