The Critical Role of (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one in Diltiazem Production
At NINGBO INNO PHARMCHEM CO.,LTD., we understand the intricate demands of pharmaceutical manufacturing. A cornerstone in the production of cardiovascular medications is the precise synthesis of Active Pharmaceutical Ingredients (APIs). One such critical component is (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one, identified by CAS number 42399-49-5. This compound is not merely a chemical entity; it is a vital pharmaceutical intermediate that underpins the reliable production of Diltiazem hydrochloride.
Diltiazem hydrochloride is a well-established calcium channel blocker, widely prescribed for managing hypertension, angina pectoris, and certain heart rhythm disorders. The efficacy and safety of this medication directly correlate with the purity and stereochemical integrity of its precursors. Our product, (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one, is manufactured to meet rigorous quality standards, boasting a minimum purity of 98.0%. This high purity level is essential to minimize potential impurities in the final API and to ensure predictable therapeutic outcomes for patients. By sourcing reliable API intermediates like this one, pharmaceutical companies can maintain the highest standards of drug quality and patient safety.
The chemical structure of this benzothiazepinone derivative is complex, featuring specific chiral centers that dictate its pharmacological activity. The (2S-cis) configuration is paramount, as it is the correct stereoisomer required for effective Diltiazem synthesis. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing materials with precise stereochemical control. This focus on quality and accuracy in supplying pharmaceutical intermediates helps our clients navigate the complexities of drug development and manufacturing. We are dedicated to supporting the pharmaceutical industry by offering high-quality building blocks that facilitate the efficient and safe production of life-saving medications. If you are looking to buy this crucial intermediate, consider NINGBO INNO PHARMCHEM CO.,LTD. for consistent quality and supply.
Perspectives & Insights
Silicon Analyst 88
“The (2S-cis) configuration is paramount, as it is the correct stereoisomer required for effective Diltiazem synthesis.”
Quantum Seeker Pro
“This focus on quality and accuracy in supplying pharmaceutical intermediates helps our clients navigate the complexities of drug development and manufacturing.”
Bio Reader 7
“We are dedicated to supporting the pharmaceutical industry by offering high-quality building blocks that facilitate the efficient and safe production of life-saving medications.”