The Role of Boc-11-Aminoundecanoic Acid in PROTAC Synthesis
In the rapidly evolving field of targeted drug discovery, PROTACs (Proteolysis Targeting Chimeras) have emerged as a revolutionary modality. These bifunctional molecules work by hijacking the cell's natural protein degradation machinery to eliminate disease-causing proteins. Central to the design and efficacy of PROTACs are the linker molecules that connect the target protein ligand to the E3 ligase ligand. Among these crucial components, Boc-11-aminoundecanoic acid (CAS 10436-25-6) stands out as a versatile and widely used building block.
As a leading manufacturer and supplier of high-quality chemical intermediates from China, we understand the critical role that reliable materials play in advanced research. Boc-11-aminoundecanoic acid, characterized by its 11-carbon chain terminating in a Boc-protected amine and a carboxylic acid group, offers a unique combination of properties ideal for PROTAC synthesis. The long alkyl chain provides flexibility and appropriate spacing, while the protected amine and carboxylic acid functionalities allow for facile conjugation with other molecular components.
Researchers and pharmaceutical companies looking to buy Boc-11-aminoundecanoic acid for their PROTAC development projects will find its structure particularly advantageous. The tert-butyloxycarbonyl (Boc) protecting group is easily removable under mild acidic conditions, revealing the free amine ready for coupling reactions, often via amide bond formation. This makes it an efficient intermediate for custom synthesis and large-scale manufacturing of PROTAC molecules.
The importance of sourcing high-purity intermediates cannot be overstated in drug discovery. Our commitment as a dedicated Boc-11-aminoundecanoic acid supplier ensures that our product meets stringent quality standards, with a typical purity of 97% or higher. This consistency is vital for achieving reproducible results and ensuring the overall quality of the final PROTAC therapeutic candidates. We offer competitive Boc-11-aminoundecanoic acid prices, reflecting our position as a direct manufacturer in China, enabling cost-effective research and development.
For those in the pharmaceutical and biotechnology sectors, exploring efficient synthesis routes and reliable material sourcing is paramount. If you are searching for an experienced 11-(Boc-amino)undecanoic acid supplier for your PROTAC linker chemistry, or need a dependable source for CAS 10436-25-6, we invite you to inquire. We are dedicated to supporting your scientific endeavors with premium chemical intermediates and responsive customer service. Contact us today to discuss your requirements and obtain a quotation for Boc-11-Aun-OH for PROTAC synthesis.
Perspectives & Insights
Core Pioneer 24
“The importance of sourcing high-purity intermediates cannot be overstated in drug discovery.”
Silicon Explorer X
“Our commitment as a dedicated Boc-11-aminoundecanoic acid supplier ensures that our product meets stringent quality standards, with a typical purity of 97% or higher.”
Quantum Catalyst AI
“This consistency is vital for achieving reproducible results and ensuring the overall quality of the final PROTAC therapeutic candidates.”